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FKBP5 / FKBP51
FK506 binding protein 5
FKBP5 / FKBP51 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
| Gene Name: | FK506 binding protein 5 |
| Synonyms: | FKBP5, 51 kd fk506-binding protein, 51 kDa FK506-binding protein, 51 kDa FK506-binding protein 5, 51 kDa FKBP, AIG6, Androgen-regulated protein 6, FKBP-51, FKBP-5, FKBP51, FF1 antigen, FK506 binding protein 5, p54, Ptg-10, Rotamase, T-cell FK506-binding protein, PPIase, PPIase FKBP5, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin |
| Target Sequences: | NM_004117 NP_004108.1 Q13451 |
Publications (1)
1
Regulation of Serine-Threonine Kinase Akt Activation by NAD+<sup>-Dependent Deacetylase SIRT7. Yu J, Qin B, Wu F, Qin S, Nowsheen S, Shan S, Zayas J, Pei H, Lou Z, Wang L. Cell reports. 2017 January;18:1229-1240. [Full Text Article]
[PubMed:28147277]
[PMC:PMC5298804]
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Saliva, Serum, Tissue Homogenates
1 Plate/$783
Wheat Germ Extract
GST, N-terminus
76.01 kDa
10 µg/$479; 25 µg/$670
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal (aa326-375) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
E. coli
His
52.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
FKBP5 / FKBP51 Mouse anti-Human Monoclonal (OTI3E9) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
FKBP5 / FKBP51 Mouse anti-Human Monoclonal (Carrier-free) (OTI3E9) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal (aa407-457) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC-P, IP, WB
Unconjugated
50 µl/$317; 100 µl/$375; 200 µl/$473
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal (aa208-257) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
FKBP5 / FKBP51 Mouse anti-Human Polyclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µg/$705
HEK 293 Cells
Myc-DDK (Flag)
51 kDa
20 µg/$1,107
E. coli
His-GST
78.1 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
FKBP5 / FKBP51 Mouse anti-Human Monoclonal (Hi51B) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Human
ICC, IF, WB
Unconjugated
25 µg/$323; 100 µg/$452
FKBP5 / FKBP51 Mouse anti-Human Monoclonal (APC) (Hi51B) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Human
ICC, IF, WB
APC Conjugated
100 µg/$488
FKBP5 / FKBP51 Mouse anti-Human Monoclonal (Atto 594) (Hi51B) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Human
ICC, IF, WB
Atto 594 Conjugated
100 µg/$489
FKBP5 / FKBP51 Mouse anti-Human Monoclonal (Atto 488) (Hi51B) Antibody
Rabbit, Mouse, Dog, Rat, Hamster, Human
ICC, IF, WB
Atto 488 Conjugated
100 µg/$489
FKBP5 / FKBP51 Mouse anti-Human Monoclonal (3D1-1B10) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal (aa2-457) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
FKBP5 / FKBP51 Rabbit anti-Human Polyclonal (aa2-457) (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
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