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FCGR3A / CD16A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3A / CD16A is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
| Synonyms: | FCGR3A, CD16A, CD16a antigen, CD16, FcgammaRIIIA, FCR-10, FCRIII, Fc gamma receptor III-A, Fc-gamma RIII, Fc-gamma RIII-alpha, FCG3, IGFR3, Fc- gamma riii, Fc-gamma receptor IIIb (CD16), Fc-gamma RIIIa, FCGR3, FCRIIIA, Neutrophil-specific antigen NA, Igg fc receptor iii-1, IgG Fc receptor III-2, Igg fc receptors iii-1, FCGRIII |
| Target Sequences: | NM_000569 NP_000560.5 P08637 |
Publications (1)
1
In Vitro Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4+ T Cells Harboring Reactivated Human Immunodeficiency Virus. Desimio MG, Giuliani E, Ferraro AS, Adorno G, Doria M. Frontiers in immunology. 2018 June;9: [Full Text Article]
[PubMed:30008723]
[PMC:PMC6033996]
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FCGR3A / CD16A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FCGR3A / CD16A Mouse anti-Human Monoclonal (Azide-free) (MEM-154) Antibody
Human
Flo, Func, IP, WB
Unconjugated, Azide-free
0.1 mg/$302
FCGR3A / CD16A Mouse anti-Human Monoclonal (MEM-154) Antibody
Human
Flo, Func, IP, WB
Unconjugated
0.1 mg/$302
FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
FCGR3A / CD16A Rabbit anti-Human Polyclonal (aa225-254) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
CHO Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.3 kDa
100 µg/$721; 1 mg/$4,701
Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FCGR3A / CD16A Mouse anti-Human Monoclonal (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$302
FCGR3A / CD16A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
FCGR3A / CD16A Mouse anti-Human Monoclonal (Biotin) (MEM-154) Antibody
Human
Flo, Func, IP, WB
Biotin Conjugated
0.1 mg/$337
FCGR3A / CD16A Rabbit anti-Rat Polyclonal (aa5-241) Antibody
Rat
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
Wheat Germ Extract
GST
51.92 kDa
10 µg/$479; 25 µg/$670
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.61kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
FCGR3A / CD16A Mouse anti-Human Monoclonal (Low Endotoxin) (3G8) Antibody
Human, Non-Human Primates
Flo, Func, IHC-Fr, IP
Unconjugated, Low Endotoxin
0.1 mg/$302
FCGR3A / CD16A Mouse anti-Human Monoclonal (PE) (MEM-154) Antibody
Human
Flo, Func, IP, WB
PE Conjugated
100 Tests/$365
FCGR3A / CD16A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
FCGR3A / CD16A Mouse anti-Rat Monoclonal Antibody
Rat
ELISA
Unconjugated
100 µl/$412
FCGR3A / CD16A Mouse anti-Human Monoclonal (N418) Antibody
Human, Monkey, Baboon, Cynomolgus, Marmoset
Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$468
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
21.7 kDa
100 µg/$843
HEK 293 Cells
Myc-DDK (Flag)
32.64 kDa
100 µg/$494
FCGR3A / CD16A Mouse anti-Human Monoclonal (Low Endotoxin) (MEM-154) Antibody
Human
Flo, Func, IP, WB
Unconjugated, Low Endotoxin
0.1 mg/$302
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