FBXW11

F-box and WD repeat domain containing 11

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. SCF(FBXW11) mediates the ubiquitination of phosphorylated CTNNB1 and participates in Wnt signaling. SCF(FBXW11) mediates the ubiquitination of phosphorylated NFKBIA, which degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription. SCF(FBXW11) mediates the ubiquitination of IFNAR1. Involved in the oxidative stress-induced a ubiquitin-mediated decrease in RCAN1. Mediates the degradation of CDC25A induced by ionizing radiation in cells progressing through S phase and thus may function in the intra-S-phase checkpoint. Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and phosphorylated PER2. Is target of human immunodeficiency virus type 1 (HIV-1) protein VPU to polyubiquitinate and deplete BST2 from cells and antagonize its antiviral action.

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Products

Antibodies (29)

Proteins (8)

Type

Over-Expression Lysate (6)

Primary (29)

Recombinant (2)

Target

FBXW11 (37)

Reactivity

Human (29)

Mouse (11)

Rat (6)

Bat (6)

Bovine (4)

Chicken (4)

Chimpanzee (6)

Dog (7)

Gibbon (3)

Guinea pig (6)

Horse (3)

Monkey (7)

Rabbit (6)

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Application

IHC (12)

IHC-P (3)

WB (21)

Flo (7)

ELISA (16)

ICC (1)

IF (9)

Peptide-ELISA (1)

Host

rabbit (23)

mouse (6)

Isotype

IgG (20)

IgG2b,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (23)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (13)

Epitope

aa168-196 (7)

N-Terminus (5)

aa38-87 (4)

aa1-140 (1)

aa335-524 (1)

Publications

No (37)

Tag

GST (1)

Myc-DDK (Flag) (7)

Species

Human (5)

Source

293T Cells (3)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

FBXW11 Antibody LS-C482886

Antibody:

FBXW11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

Select

FBXW11 Antibody (aa38-87) LS-C80549

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa38-87) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

FBXW11 Antibody (N-Terminus) LS-C60083

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Human, Monkey

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$567

Select

FBXW11 Antibody (aa168-196) LS-C166093

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa168-196) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

FBXW11 Antibody (aa168-196) LS-C321330

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa168-196) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

FBXW11 Antibody (aa168-196, Biotin) LS-C222531

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa168-196) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

FBXW11 Antibody (aa168-196, FITC) LS-C222530

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa168-196) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

FBXW11 Antibody (aa168-196, APC) LS-C222528

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa168-196) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

FBXW11 Antibody (aa168-196, Azide-free, HRP) LS-C222529

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa168-196) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

FBXW11 Antibody (aa168-196, PE) LS-C222533

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa168-196) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

FBXW11 Antibody LS-C409333

Antibody:

FBXW11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

FBXW11 Antibody LS-C766553

Antibody:

FBXW11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

FBXW11 Antibody (aa1-140) LS-C380208

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa1-140) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

FBXW11 Antibody LS-C308007

Antibody:

FBXW11 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

100 µg/$705

Select

FBXW11 Antibody (HRP) LS-C542123

Antibody:

FBXW11 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

100 µl/$904

Select

FBXW11 Antibody (Biotin) LS-C521990

Antibody:

FBXW11 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

FBXW11 Antibody (FITC) LS-C532034

Antibody:

FBXW11 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

FITC Conjugated

Price:

100 µl/$904

Select

FBXW11 Antibody (PE) LS-C650234

Antibody:

FBXW11 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

PE Conjugated

Price:

100 µl/$904

Select

FBXW11 Antibody (APC) LS-C513775

Antibody:

FBXW11 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

FBXW11 Antibody (aa335-524) LS-C348836

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (aa335-524) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µl/$332

Select

FBXW11 Antibody LS-C665554

Antibody:

FBXW11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

FBXW11 Antibody LS-C803389

Antibody:

FBXW11 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

FBXW11 Antibody (N-Terminus) LS-C80570

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

FBXW11 Antibody (N-Terminus, Biotin) LS-C445051

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Chicken, Rabbit, Mouse, Dog, Guinea pig, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

FBXW11 Antibody (N-Terminus, FITC) LS-C445052

Antibody:

FBXW11 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Chicken, Rabbit, Mouse, Dog, Guinea pig, Bat, Human, Monkey, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

Viewing 1-25 of 37 product results

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