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FBXO32 / Fbx32

F-box protein 32

FBXO32 / Fbx32 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: F-box protein 32
Family/Subfamily: F-Box
Synonyms: FBXO32, Atrogin 1, ATROGIN1, F-box protein 32, F-box only protein 32, Fbx32, Muscle atrophy F-box protein, MAFBX, Atrogin-1
Target Sequences: NM_058229 NP_478136.1 Q969P5

Publications (1)

1
FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation. Zhou H, Liu Y, Zhu R, Ding F, Wan Y, Li Y, Liu Z. Oncogene. 2017 June;36:3312-3321. (Human) [Full Text Article] [PubMed:28068319] [PMC:PMC5926769] Related Antibodies: LS-B9748.

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Antibodies (30)
ELISA Kits (11)
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Over-Expression Lysate (4)
Primary (30)
Recombinant (3)
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FBXO32 / Fbx32 (48)
Human (33)
Mouse (16)
Rat (12)
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Dog (4)
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Guinea pig (3)
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IHC (10)
IHC-P (4)
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Peptide-ELISA (3)
rabbit (22)
mouse (7)
goat (1)
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monoclonal mc (6)
polyclonal pc (24)
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FBXO32 / Fbx32 Antibody - Anti-FBXO32 / MAFBX / Atrogin 1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
100 µl/$485
FBXO32 / Fbx32 Antibody - Anti-FBXO32 / MAFBX / Atrogin 1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FBXO32 / Fbx32 Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody
Chicken, Bovine, Rat, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
FBXO32 / Fbx32 Antibody - Anti-FBXO32 / MAFBX / Atrogin 1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FBXO32 / Fbx32 Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody
Chicken, Bovine, Rat, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
FBXO32 / Fbx32 Antibody - Anti-FBXO32 / MAFBX / Atrogin 1 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FBXO32 / Fbx32 Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody
Chicken, Bovine, Rat, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Gibbon, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
FBXO32 / Fbx32 Antibody - FBXO32 antibody (0.1 ug/ml) staining of Human Skeletal Muscle lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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FBXO32 / Fbx32 Goat anti-Human Polyclonal (aa70-82) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
FBXO32 / Fbx32 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
39.063 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
FBXO32 / Fbx32 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
FBXO32 / Fbx32 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
39.06 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FBXO32 / Fbx32 Protein - Recombinant  F-Box Protein 32 By SDS-PAGE
Select
E. coli
His-T7
27.2 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,585
FBXO32 / Fbx32 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer tissue using FBXO32 antibody.
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
FBXO32 / Fbx32 Antibody - 1:100 staining mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FBXO32 / Fbx32 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using FBXO32 Polyclonal Antibody at dilution of 1:45(×200)
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
FBXO32 / Fbx32 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using FBXO32 Polyclonal Antibody at dilution of 1:35(×200)
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
FBXO32 / Fbx32 Antibody - Immunohistochemistry of paraffin-embedded Rat liver using FBXO32 Polyclonal Antibody at dilution of 1:100 (40x lens).
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
FBXO32 / Fbx32 Antibody - All lanes: Anti-FBXO32 Antibody (N-Term) at 1:2000 dilution. Lane 1: HeLa whole cell lysate. Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 42 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal (aa17-49) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
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FBXO32 / Fbx32 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µg/$705
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FBXO32 / Fbx32 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$904
Select
FBXO32 / Fbx32 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
100 µl/$904
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FBXO32 / Fbx32 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA
PE Conjugated
100 µl/$904
Select
FBXO32 / Fbx32 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA
APC Conjugated
100 µl/$904
Select
FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
FBXO32 / Fbx32 Antibody - Western blot analysis of extracts of Mouse heart cell lines, using FBXO32 antibody.
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389; 200 µl/$503
FBXO32 / Fbx32 Antibody - Western blot of FBXO32 / Fbx32 antibody.
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal (aa1-201) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561
FBXO32 / Fbx32 Antibody - Western blot analysis of FBXO32 expression in mouse heart (A); mouse skeletal muscle (B) whole cell lysates.
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FBXO32 / Fbx32 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
Viewing 1-25 of 48 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).