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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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F5 / Factor Va Antibody LS‑C147779
Factor Va antibody LS-C147779 is an unconjugated rabbit polyclonal antibody to human Factor Va (F5). Validated for ID and IE.
Antibody
Catalog
Size
Price
LS-C147779-1
1 ml
$415

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Product Description

Factor Va antibody LS-C147779 is an unconjugated rabbit polyclonal antibody to human Factor Va (F5). Validated for ID and IE.
About F5 / Factor Va
F5 / Factor Va is an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. P12259 NM_000130 NP_000121.2

F5 Antibody, Activated protein C cofactor Antibody, Factor V Leiden Antibody, FVL Antibody, Factor Va Antibody, RPRGL1 Antibody, THPH2 Antibody, Coagulation factor V Antibody, PCCF Antibody, Proaccelerin, labile factor Antibody


Specifications

Target
Human F5 / Factor Va
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity absorbed
Modifications
Unmodified
Applications
  • Immunodiffusion
  • Immunoelectrophoresis
Immunogen
F5 / Factor Va antibody was raised against human Factor V
Specificity
Human F5 / Factor Va. The defined antibody reactivity is restricted to Factor V, its activated form (Fva) and degradation products. In immunoelectrophoresis, bidimensional electrophoresis, and double radial immunodiffusion (Ouchterlony) against plasma, a single precipitin line is obtained which shows a reaction of identity with the precipitated purified Factor V. No precipitation is obtained with Factor V-depleted plasma and serum. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however in double radial immunodiffusion a reaction with Rhesus monkey has been observed.
Usage
This product is intended for use in precipitating techniques as electroimmunodiffusion, immunoelectrophoresis, single and double radial immunodiffusion (Mancini, Ouchterlony) and neutralization assay. The presence of non-precipitating antibodies has not been assayed. If used in more sensitive test procedures or as catching or detection antibody in solid phase immunoassays specificity controls should always be include. Plasma samples and all assay components must contain EDTA to stabilize the proteins.
Presentation
Lyophilized antiserum
Reconstitution
1 ml Sterile distilled water 1 ml
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/25/2018

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