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Catalog Number Size Price
LS-C147235-1 1 ml $405 
Antibody

Polyclonal Goat anti‑Human F12 / Factor XII Antibody LS‑C147235

Polyclonal Goat anti‑Human F12 / Factor XII Antibody LS‑C147235

Antibody:
Goat Polyclonal to Human F12 / Factor XII
Application:
ID
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$405 
LS-C147235-1
1 ml
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Goat Polyclonal to Human F12 / Factor XII
Application:
ID
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Factor XII antibody LS-C147235 is an unconjugated goat polyclonal antibody to human Factor XII (F12). Validated for ID.
Target
Human F12 / Factor XII
Synonyms
F12 | Beta-factor XIIa part 2 | Beta-factor XIIa part 1 | Coagulation factor XII | F12 deficiency | Factor XII | Factor XII deficiency | HAE3 | HAEX | Hageman factor | HAF
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity absorbed
Modifications
Unmodified
Applications
  • Immunodiffusion
Immunogen
Human Factor XII
Specificity
Human F12 / Factor XII. The defined antibody reactivity is restricted to FXII, FXIIa and complexes of FXIIa with other proteins. In immunoelectrophoresis, bi-dimensional electrophoresis and radial immunodiffusion (Ouchterlony) against normal plasma, a single precipitin line is obtained which shows a reaction of identity with precipitated purified Factor XII. No reaction is obtained with FXII-depleted plasma. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however in immunoelectrophoresis a reaction with Rhesus monkey plasma has been found.
Usage
This antiserum is primarily intended for the measurement of Factor XII in human plasma using the EID-method (Laurell): a specially purified agarose solution containing between 1 and 2% antiserum is poured onto a glass plate and allowed to gel. Plasma containing FXII is incorporated into a series of wells and electrophoresis is performed. Rockets due to antigen/antibody reaction are measured. The height of the rocket is directly proportional to the FXII concentration in the plasma.
Presentation
Lyophilized antiserum
Reconstitution
Use 1 ml of sterile Distilled water.
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About F12 / Factor XII
P00748 NM_000505 NP_000496.2

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Requested From: United States
Date Requested: 5/24/2020