EYA1

eyes absent homolog 1 (Drosophila)

Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears. Together with SIX1, it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2.

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Products

Antibodies (29)

Proteins (13)

Type

Over-Expression Lysate (12)

Primary (29)

Recombinant (1)

Target

EYA1 (42)

Reactivity

Human (23)

Mouse (21)

Rat (12)

Bat (9)

Bovine (9)

Chicken (3)

Chimpanzee (6)

Dog (6)

Gibbon (9)

Guinea pig (9)

Hamster (1)

Horse (6)

Monkey (7)

Orangutan (3)

Pig (6)

Rabbit (10)

Xenopus (3)

Zebrafish (4)

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Application

IHC (1)

WB (25)

ELISA (9)

IF (2)

Peptide-ELISA (1)

Host

rabbit (28)

goat (1)

Isotype

IgG (17)

Clonality

polyclonal pc (29)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (5)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (1)

Unconjugated (12)

Epitope

aa1-30 (7)

C-Terminus (4)

N-Terminus (4)

aa201-250 (4)

Internal (1)

aa271-283 (1)

Publications

No (42)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (12)

Species

Human (7)

Source

293T Cells (6)

HEK 293 Cells (6)

Wheat Germ Extract (1)

Select

EYA1 Antibody (aa1-30) LS-C167870

Antibody:

EYA1 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

EYA1 Antibody (Internal) LS-C354355

Antibody:

EYA1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Zebrafish, Rat, Mouse, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

EYA1 Antibody LS-C665459

Antibody:

EYA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

EYA1 Antibody LS-C813849

Antibody:

EYA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

EYA1 Antibody LS-C672447

Antibody:

EYA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

EYA1 Antibody (aa1-30) LS-C321234

Antibody:

EYA1 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

EYA1 Antibody (aa1-30, Biotin) LS-C259312

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

EYA1 Antibody (aa1-30, FITC) LS-C259313

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

EYA1 Antibody (aa1-30, APC) LS-C259311

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

EYA1 Antibody (aa1-30, Azide-free, HRP) LS-C259314

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

EYA1 Antibody (aa1-30, PE) LS-C259316

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

EYA1 Antibody (aa271-283) LS-C108927

Antibody:

EYA1 Goat anti-Human Polyclonal (aa271-283) Antibody

Reactivity:

Rabbit, Mouse, Rat, Hamster, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

EYA1 Antibody (aa201-250) LS-C151185

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa201-250) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

EYA1 Antibody (aa201-250, HRP) LS-C427894

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa201-250) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

EYA1 Antibody (aa201-250, Biotin) LS-C427892

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa201-250) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

EYA1 Antibody (aa201-250, FITC) LS-C427893

Antibody:

EYA1 Rabbit anti-Mouse Polyclonal (aa201-250) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

EYA1 Antibody LS-C411068

Antibody:

EYA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

EYA1 Antibody (C-Terminus) LS-C107835

Antibody:

EYA1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

EYA1 Antibody (C-Terminus, HRP) LS-C439523

Antibody:

EYA1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

EYA1 Antibody (C-Terminus, Biotin) LS-C439521

Antibody:

EYA1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

EYA1 Antibody (C-Terminus, FITC) LS-C439522

Antibody:

EYA1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Pig, Horse, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

EYA1 Antibody (N-Terminus) LS-C201257

Antibody:

EYA1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

EYA1 Antibody (N-Terminus, HRP) LS-C427890

Antibody:

EYA1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Orangutan, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

EYA1 Antibody (N-Terminus, FITC) LS-C427891

Antibody:

EYA1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Bat, Gibbon, Chimpanzee, Orangutan, Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

Select

EYA1 Antibody LS-C411854

Antibody:

EYA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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