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Catalog Number Size Price
LS-C357880-100 100 Tests (0.1 mg/ml) $522 
ESR2 / ER Beta Antibody - Estrogen Receptor beta antibody ERb455 FACS

Monoclonal Mouse anti‑Human ESR2 / ER Beta Antibody (clone ERb455, C‑Terminus, IF) LS‑C357880

Monoclonal Mouse anti‑Human ESR2 / ER Beta Antibody (clone ERb455, C‑Terminus, IF) LS‑C357880

Antibody:
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (ERb455) Antibody
Application:
IF, Flo
Reactivity:
Human, Monkey, Mouse, Rat, Horse, Pig, Sheep
Format:
Unconjugated, Unmodified
Price
Catalog Number
$522
LS-C357880-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
ESR2 / ER Beta Mouse anti-Human Monoclonal (C-Terminus) (ERb455) Antibody
Application:
IF, Flo
Reactivity:
Human, Monkey, Mouse, Rat, Horse, Pig, Sheep
Format:
Unconjugated, Unmodified

Specifications

Description
ER Beta antibody LS-C357880 is an unconjugated mouse monoclonal antibody to ER Beta (ESR2) (C-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for Flow and IF.
Target
Human ESR2 / ER Beta
Synonyms
ESR2 | ESTRB | ER Beta | ERbeta | ER-BETA | ESR-BETA | ESRB | Estrogen receptor 2 (ER beta) | NR3A2 | Estrogen receptor beta | Estrogen receptor beta 4
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat, Horse, Pig, Sheep (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Clone
ERb455
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
The C-Terminus fragment of recombinant human Estrogen Receptor beta protein.
Epitope
C-Terminus
Specificity
Human ESR2 / ER Beta
Applications
  • Immunofluorescence (1:50 - 1:100)
  • Flow Cytometry
Usage
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including alpha and beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER alpha and beta are differentially activated by various ligands. Ligand interaction triggers a cascade of events, including dissociation from heat shock proteins, recepter dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and beta may be regulated by distinct mechanisms even though they share many functional characteristics.
Presentation
0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ESR2 / ER Beta
Q92731 NM_001437 NP_001428.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/5/2021