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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ESPL1 / Separase Antibody (HRP) LS‑C500889
Separase antibody LS-C500889 is an HRP-conjugated rabbit polyclonal antibody to human Separase (ESPL1). Validated for ELISA.
Antibody
Catalog
Size
Price
LS-C500889-50
50 µg
$285
LS-C500889-100
100 µg
$385

Popular ESPL1 / Separase Products

IHC of Separase (A795) pAb in paraffin-embedded human colon carcinoma tissue.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Western blot of Separase antibody
Species: Human, Mouse
Applications: IHC, Immunofluorescence, Western blot, ELISA
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Anti-Separase antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-ESPL1 / Separase antibody IHC of human tonsil, mitotic figures. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

Separase antibody LS-C500889 is an HRP-conjugated rabbit polyclonal antibody to human Separase (ESPL1). Validated for ELISA.

Specifications

Target
Human ESPL1 / Separase
Synonyms
ESPL1, ESP1, Extra spindle poles like 1, KIAA0165, Caspase-like protein ESPL1, SEPA, Separase, Separin
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
Recombinant Human Separin protein (1292-1495AA)
Specificity
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ESPL1 / Separase
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. Q14674 NM_012291 NP_036423.4


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Requested From: United States
Date Requested: 11/16/2018

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