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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ERGIC‑53 / LMAN1 Antibody (aa198‑475, Biotin) LS‑C687243
LMAN1 antibody LS-C687243 is a biotin-conjugated rabbit polyclonal antibody to human LMAN1 (ERGIC-53). Validated for IHC and WB.
Catalog
Size
Price
LS-C687243-20
20 µl
$205
LS-C687243-100
100 µl
$265
LS-C687243-200
200 µl
$315
LS-C687243-1
1 ml
$575
LS-C687243-10
10 ml
$2,310

Popular ERGIC-53 / LMAN1 Products

Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken
Applications: Western blot
IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Species: Human, Monkey, Rat, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:50.
Species: Human, Monkey, Rat, Dog
Applications: IHC, IHC - Paraffin, Western blot
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Species: Human, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry

Product Description

LMAN1 antibody LS-C687243 is a biotin-conjugated rabbit polyclonal antibody to human LMAN1 (ERGIC-53). Validated for IHC and WB.

Specifications

Target
Human ERGIC-53 / LMAN1
Synonyms
LMAN1, ERGIC53, F5F8D, gp58, ERGIC-53, FMFD1, Lectin mannose-binding 1, MCFD1, MR60, Protein ERGIC-53, Lectin, mannose-binding, 1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with Biotin, FITC, FITC, Cy3, HRP, APC, PE, APC, Cy7.
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Recombinant LMAN1 (Pro198-Cys475)
Epitope
aa198-475
Specificity
The antibody is a rabbit polyclonal antibody raised against LMAN1. It has been selected for its ability to recognize LMAN1 in immunohistochemical staining and western blotting.
Presentation
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Storage
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
Restrictions
For research use only.
About ERGIC-53 / LMAN1
ERGIC-53 / LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. P49257 NM_005570 NP_005561.1


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Images

Western blot

Western blot of ERGIC-53 / LMAN1 antibody.
Western blot of ERGIC-53 / LMAN1 antibody.

Western blot

Western blot of ERGIC-53 / LMAN1 antibody.
Western blot of ERGIC-53 / LMAN1 antibody.

Western blot

Western blot of ERGIC-53 / LMAN1 antibody.
Western blot of ERGIC-53 / LMAN1 antibody.

Western blot

Western blot of ERGIC-53 / LMAN1 antibody.
Western blot of ERGIC-53 / LMAN1 antibody.

Requested From: United States
Date Requested: 11/13/2018

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