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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ERCC6 / CSB Antibody (aa141‑190) LS‑C291261
CSB antibody LS-C291261 is an unconjugated rabbit polyclonal antibody to human CSB (ERCC6). Validated for IHC and Peptide-ELISA.
Antibody
Catalog
Size
Price
LS-C291261-50
50 µl (1 mg/ml)
$265
LS-C291261-100
100 µl (1 mg/ml)
$325

Popular ERCC6 / CSB Products

Antibody
Species: Human
Applications: Western blot
Antibody
Species: Human
Applications: Western blot, ELISA
Immunohistochemical analysis of ERCC6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Anti-CSB / ERCC6 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
Species: Human
Applications: IHC, ELISA

Product Description

CSB antibody LS-C291261 is an unconjugated rabbit polyclonal antibody to human CSB (ERCC6). Validated for IHC and Peptide-ELISA.

Specifications

Target
Human ERCC6 / CSB
Synonyms
ERCC6, ARMD5, Cockayne syndrome B protein, Cockayne syndrome protein CSB, COFS, CSB, Rad26 homolog, ATP-dependent helicase ERCC6, CKN2, COFS1, RAD26, UVSS1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Peptide Enzyme-Linked Immunosorbent Assay (1:10000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ERCC6 / CSB antibody was raised against synthetic peptide derived from human ERCC6. (AA Range: 141-190)
Epitope
aa141-190
Specificity
ERCC6 Antibody detects endogenous levels of ERCC6.
Usage
Western Blot: Predicted MW 168 kDa
Presentation
PBS, pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
About ERCC6 / CSB
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. Q03468 NM_000124 NP_000115.1


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Requested From: United States
Date Requested: 11/15/2018

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