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Catalog Number Size Price
LS-C11318-0.1 0.1 mg (1 mg/ml) $385 
Antibody

Monoclonal Rat anti‑Human Endothelin Antibody (clone 3G10, C‑Terminus, IHC) LS‑C11318

Monoclonal Rat anti‑Human Endothelin Antibody (clone 3G10, C‑Terminus, IHC) LS‑C11318

Antibody:
Endothelin Rat anti-Human Monoclonal (C-Terminus) (3G10) Antibody
Application:
IHC, IHC-Fr, IRMA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$385
LS-C11318-0.1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
Endothelin Rat anti-Human Monoclonal (C-Terminus) (3G10) Antibody
Application:
IHC, IHC-Fr, IRMA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Endothelin antibody LS-C11318 is an unconjugated rat monoclonal antibody to human Endothelin (C-Terminus). Validated for IHC and IRMA.
Target
Human Endothelin
Host
Rat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Clone
3G10
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to the C-Terminus of human endothelin (C, H, L, D, I, I, W), conjugated to BSA.
Epitope
C-Terminus
Specificity
Reacts with the C terminal of endothelins 1, 2 and 3. 3G10 does not react with the endothelin precursor molecule, big endothelin. The endothelins are potent vasoconstrictors and critical components in the progression of pulmonary arterial hypertension a devastating and rapidly progressive condition that leads to right ventricular strain and dysfunction.
Applications
  • IHC
  • IHC - Frozen
  • Immunoradiometric assay
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Immunohistology: Frozen sections processed with dry acetone are recommended. Paraformaldehyde is not recommended as it destroys the epitope.
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

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Requested From: United States
Date Requested: 4/24/2024