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Catalog Number Size Price
LS-C52315-0.2 0.2 mg $401 
LS-C52315-0.5 0.5 mg $482 
Antibody

Monoclonal Mouse anti‑Human EMA / MUC1 Antibody (clone M10H6, IF) LS‑C52315

Monoclonal Mouse anti‑Human EMA / MUC1 Antibody (clone M10H6, IF) LS‑C52315

Note: This antibody replaces LS-C72868
Antibody:
EMA / MUC1 Mouse anti-Human Monoclonal (M10H6) Antibody
Application:
IF
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$401
LS-C52315-0.2
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
EMA / MUC1 Mouse anti-Human Monoclonal (M10H6) Antibody
Application:
IF
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
MUC1 antibody LS-C52315 is an unconjugated mouse monoclonal antibody to human MUC1 (EMA). Validated for IF.
Target
Human EMA / MUC1
Synonyms
MUC1 | CA15-3 | CD227 | Carcinoma-associated mucin | CD227 antigen | DF3 antigen | Episialin | Epithelial membrane antigen | H23 antigen | H23AG | Krebs von den Lungen-6 | MAM6 | MUC1/ZD | MUC-1/SEC | Mucin-1 | Pem | KL-6 | MUC-1/X | Tumor-associated mucin | Peanut-reactive urinary mucin | Polymorphic epithelial mucin | PUM | EMA | MUC-1 | Mucin 1, transmembrane
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Monoclonal
Clone
M10H6
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
High molecular weight (>300 kD) glycoprotein.
Specificity
VNTR5 and VNTR20 recombinant unglycosylated fragments of MUC1 protein and underglycosylated MUC1 prepared from tumor fluids or as a result of chemical treatment of human milk MUC1. These MAbs do not recognize natural MUC1 protein isolated from human milk by affinity purification on carbohydrate epitope specific MAbs and belong to MAb cluster 1-4 according to ISOMB TD-4 classification. No cross-reactivity with egg white avidin. MAbs M4H2, M2F1, M2C5, M2E104 and M3A106: Affinity >1 X 108 all MAbs. MAbs bind with high efficiency with different epitopes within the VNTR tandem repeat peptide region of MUC1 molecule, which have different conmations and peptide- carbohydrate compositions. MAb M4H2 reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein (and very weakly with monomeric MUC1 peptide), with deglycosylated and underglycosylated natural MUC1 (but not with completely glycosylated natural milk MUC1). MAbs M2F1, M2C5, M2E104, M3A106 efficiently recognize underglycosylated and natural MUC1 protein isolated from human milk by affinity chromatography. All these MAbs belong to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Non cross-reactive with normal serum proteins and human tissues of non-epithelial origin.
Applications
  • Immunofluorescence
Presentation
PBS, pH 7.4, 0.1% Sodium Azide
Storage
Store at 4°C. Avoid freezing.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About EMA / MUC1
P15941 NM_002456 NP_002447.4

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Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 8/18/2022