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EMA / MUC1
mucin 1, cell surface associated
EMA / MUC1 is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
| Gene Name: | mucin 1, cell surface associated |
| Family/Subfamily: | Mucin , not assigned-Mucin |
| Synonyms: | MUC1, CA15-3, CD227, Carcinoma-associated mucin, CD227 antigen, DF3 antigen, Episialin, Epithelial membrane antigen, H23 antigen, H23AG, Krebs von den Lungen-6, MAM6, MUC1/ZD, MUC-1/SEC, Mucin-1, Pem, KL-6, MUC-1/X, Tumor-associated mucin, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, PUM, EMA, MUC-1, Mucin 1, transmembrane |
| Target Sequences: | NM_002456 NP_002447.4 P15941 |
Publications (7)
1
Aberrant cystatin-C expression in blood from patients with breast cancer is a suitable marker for monitoring tumor burden. Kwon WS, Kim TS, Nahm CH, Moon Y, Kim JJ. Oncology letters. 2018 November;16:5583-5590. [Full Text Article]
[PubMed:30344712]
[PMC:PMC6176264]
2
Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth. Elena Zagato , Chiara Pozzi , Alice Bertocchi, Tiziana Schioppa, Fabiana Saccheri, Silvia Guglietta, Bruno Fosso, Laura Melocchi, Giulia Nizzoli, Jacopo Troisi, Marinella Marzano, Bianca Oresta, Ilaria Spadoni, Koji Atarashi, Sara Carloni, Stefania Arioli, Giulia Fornasa, Francesco Asnicar, Nicola Segata, Simone Guglielmetti, Kenya Honda, Graziano Pesole, William Vermi, Giuseppe Penna, Maria Rescigno. Nature microbiology. 2020 March;5:511-524. [Full Text Article]
[PubMed:31988379]
[PMC:PMC7048616]
Related Antibodies: LS-C343984.
3
Serum concentration of sex hormone-binding globulin in healthy volunteers and patients with breast cancer stratified by sex and age. Se Jung Park, Tae Soo Kim, Kyu Hyun Park, Woo Sun Kwon, Jin Ju Kim. Oncology letters. 2020 July;20:364-372. [Full Text Article]
[PubMed:32565962]
[PMC:PMC7285803]
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EMA / MUC1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IF, IHC, IHC-P
FITC Conjugated
50 µg/$485
EMA / MUC1 Mouse anti-Human Monoclonal (GP1.4) Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 mg/$460
EMA / MUC1 Rabbit anti-Mouse Polyclonal (aa474-630) Antibody
Mouse, Rat
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
EMA / MUC1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
EMA / MUC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
EMA / MUC1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
250 µl/$485
EMA / MUC1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
200 µg/$798
EMA / MUC1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Pig, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
Sandwich
96-Well Strip Plate
Monkey
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
E. coli
His, N-Terminal
17.2 kDa
10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$685
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
Cancer Pathology
Cancer
EMA / MUC1 Mouse anti-Human Monoclonal (VU-4H5) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$485
EMA / MUC1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, IHC-Fr, IHC-P
Unconjugated
0.5 mg/$585
EMA / MUC1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P
Unconjugated
1 mg/$1,288
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Sandwich
96-Well Microplate
Human
4.096 - 1000 mU/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
EMA / MUC1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
EMA / MUC1 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (115D8) Antibody
Human
Flo, IF, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
EMA / MUC1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
50 µl/$440
EMA / MUC1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Cancer Pathology
Cancer
EMA / MUC1 Mouse-Balb/c anti-Human Monoclonal (139H2) Antibody
Human
ELISA, EM, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$485
Cancer Pathology
Cancer
EMA / MUC1 Mouse-Balb/c anti-Human Monoclonal (139H2) Antibody
Human
ELISA, EM, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µl/$460
E. coli
His-GST
49.6 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
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