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Catalog Number Size Price
LS-C43158-0.1 0.1 mg $375 
Antibody

EIF4EBP1 / 4EBP1 Antibody (C‑Terminus) LS‑C43158

EIF4EBP1 / 4EBP1 Antibody (C‑Terminus) LS‑C43158

Note: This antibody replaces LS-C57131
Antibody:
Rabbit Polyclonal to Human EIF4EBP1 / 4EBP1
Application:
WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$375 
LS-C43158-0.1
0.1 mg
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human EIF4EBP1 / 4EBP1
Application:
WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
4EBP1 antibody LS-C43158 is an unconjugated rabbit polyclonal antibody to human 4EBP1 (EIF4EBP1 ). Validated for WB.
Target
Human EIF4EBP1 / 4EBP1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (2.5 - 5 µg/ml)
Immunogen
A 14 amino acid peptide located near human 4EBP1 carboxy-terminus. (C-TERMINAL).
Epitope
C-Terminus
Specificity
Recognizes an epitope within the C-terminal region (CT) of eukaryotic translation initiation factor 4E binding protein 1 (4EBP1), a rapamycin-sensitive downstream target of TOR (Target of rapamycin), and regulatory factor of eukaryotic mRNA translation. The association between 4EPB1 and eukaryotic translation initiation factor 4E (eIF-4E) inhibits the binding of eIF-4E with p220, thereby preventing the formation of a functional eIF-4E complex, essential for mRNA translation. Phosphorylation of 4EBP1 following stimulation by mitogens such as insulin, results in the release of eIF-4E from 4EBP1, thereby enabling the translation complex to assemble.(AHP993) has been reported as suitable for use in IHC on mouse 3T3 cell cytospins.
Usage
Western Blot: LS-C43158 detects a band of approximately 20kD in mouse 3T3 cell lysates. (predicted MW 13kD).
Presentation
PBS, 0.02% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About EIF4EBP1 / 4EBP1
Q13541 NM_004095 NP_004086.1

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Requested From: United States
Date Requested: 10/23/2019