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Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES.
Gene Name: | embryonal Fyn-associated substrate |
Synonyms: | EFS, CASS3, EFS1, EFS2, SIN, CAS3, HEFS |
Target Sequences: | NM_005864 NP_005855.1 O43281 |
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