EDR / PEG10

paternally expressed 10

This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS). While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation and apoptosis. Overexpression of this gene has been associated with several malignancies, such as hepatocellular carcinoma and B-cell lymphocytic leukemia. Knockout mice lacking this gene showed early embryonic lethality with placental defects, indicating the importance of this gene in embryonic development. Additional isoforms resulting from alternatively spliced transcript variants, and use of upstream non-AUG (CUG) start codon have been reported for this gene.

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Products

Antibodies (35)

Proteins (6)

ELISA Kits (3)

Type

Custom (1)

Over-Expression Lysate (4)

Primary (35)

Recombinant (2)

Sandwich (2)

Target

EDR / PEG10 (44)

Reactivity

Human (37)

Mouse (3)

Bovine (6)

Chimpanzee (6)

Horse (3)

Monkey (3)

Pig (5)

Rabbit (5)

Application

IHC (6)

IHC-P (3)

WB (33)

Flo (7)

ELISA (15)

ICC (2)

IF (5)

IP (3)

Peptide-ELISA (1)

Host

rabbit (24)

mouse (11)

Product Group

IHCPlus (2)

Isotype

IgG (14)

IgG1 (8)

Clonality

monoclonal mc (11)

polyclonal pc (24)

Clone

1B1C4 (2)

4C10A7 (2)

OTI1G10 (2)

Format

96-Well Strip Plate (3)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (4)

Carrier-free (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (21)

Epitope

aa1-30 (7)

aa123-172 (4)

aa324-373 (4)

Amino Acid: 1-120 (1)

aa1-325 (1)

aa325-375 (1)

Publications

No (44)

Sample Type

Plasma (2)

Serum (2)

Tissue Homogenates (1)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ EDR / PEG10 Antibody (clone 4C10A7) LS-B4105

(4.0) Rating

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal (4C10A7) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ EDR / PEG10 Antibody (clone 1B1C4) LS-B4104

(4.0) Rating

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal (1B1C4) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Human EDR / PEG10 (Sandwich ELISA) ELISA Kit - LS-F13383

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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EDR / PEG10 Antibody LS-C816946

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

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EDR / PEG10 Antibody (aa1-30) LS-C163514

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

Flo, Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

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EDR / PEG10 Antibody (Amino Acid: 1-120, clone 1B1C4) LS-C758752

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal (Amino Acid: 1-120) (1B1C4) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

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EDR / PEG10 Antibody LS-C813075

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal Antibody

Reactivity:

Rabbit, Mouse, Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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EDR / PEG10 Antibody LS-C812827

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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EDR / PEG10 Antibody LS-C753043

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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EDR / PEG10 Antibody (aa1-30) LS-C323931

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

200 µl/$734

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EDR / PEG10 Antibody (aa1-30, Biotin) LS-C266038

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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EDR / PEG10 Antibody (aa1-30, FITC) LS-C266039

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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EDR / PEG10 Antibody (aa1-30, PE) LS-C284531

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

PE Conjugated

Price:

200 µl/$952

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EDR / PEG10 Antibody (aa1-30, Azide-free, HRP) LS-C266040

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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EDR / PEG10 Antibody (aa1-30, APC) LS-C266037

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• HRP, Azide-free
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • HRP, Azide-free
  • APC

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EDR / PEG10 Antibody (clone 4C10A7) LS-C758749

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal (4C10A7) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

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EDR / PEG10 Antibody LS-C813077

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

EDR / PEG10 Antibody LS-C317712

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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EDR / PEG10 Antibody (HRP) LS-C317711

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

EDR / PEG10 Antibody (aa1-325, Biotin) LS-C317706

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (aa1-325) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

EDR / PEG10 Antibody (FITC) LS-C317709

Antibody:

EDR / PEG10 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

EDR / PEG10 Antibody LS-C393603

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$391

Select

EDR / PEG10 Antibody LS-C178289

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal Antibody

Reactivity:

Rabbit, Mouse, Pig, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

EDR / PEG10 Antibody (clone OTI1G10) LS-C794983

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal (OTI1G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

EDR / PEG10 Antibody (clone OTI1G10, Carrier-free) LS-C792108

Antibody:

EDR / PEG10 Mouse anti-Human Monoclonal (Carrier-free) (OTI1G10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Viewing 1-25 of 44 product results

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