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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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EDEM1 / EDEM Antibody LS‑C411860
EDEM antibody LS-C411860 is an unconjugated rabbit polyclonal antibody to EDEM (EDEM1) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C411860-100
100 µl (1 mg/ml)
$385

Popular EDEM1 / EDEM Products

721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Bovine, Guinea pig, Hamster, Pig, Rabbit
Applications: Western blot
Western blot analysis of EDEM1 expression in HEK293T (A); Raw264.7 (B); PC12 (C) whole cell lysates.
Species: Human, Monkey, Mouse, Rat, Bovine, Pig, Rabbit
Applications: Western blot
Antibody
Species: Human
Applications: Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

EDEM antibody LS-C411860 is an unconjugated rabbit polyclonal antibody to EDEM (EDEM1) from human, mouse and rat. Validated for WB.

Specifications

Target
Human EDEM1 / EDEM
Synonyms
EDEM1, EDEM, KIAA0212
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
Immunogen
EDEM1 / EDEM antibody was raised against synthetic peptide from human EDEM1.
Specificity
EDEM1 pAb detects endogenous levels of EDEM1 protein.
Presentation
PBS, pH 7.2, 15 mM Sodium Azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About EDEM1 / EDEM
Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity. AX210604


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Images

Western blot

Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.

Western blot

Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.

Western blot

Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.

Western blot

Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.
Western blot of EDEM1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: PC12 whole cell lysate.

Requested From: United States
Date Requested: 11/16/2018

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