DR1 / NC2

down-regulator of transcription 1, TBP-binding (negative cofactor 2)

DR1 / NC2 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

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Products

Antibodies (32)

Proteins (8)

Type

Over-Expression Lysate (2)

Primary (32)

Recombinant (6)

Target

DR1 / NC2 (40)

Reactivity

Human (31)

Mouse (20)

Rat (10)

Bat (6)

Bovine (6)

Chicken (6)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Guinea pig (3)

Hamster (6)

Horse (6)

Monkey (6)

Pig (6)

Rabbit (6)

Xenopus (6)

Zebrafish (6)

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Application

IHC (6)

IHC-P (3)

WB (32)

ELISA (8)

ICC (1)

IF (4)

IP (1)

Host

rabbit (31)

mouse (1)

Isotype

IgG (18)

Clonality

polyclonal pc (32)

Format

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (14)

Epitope

aa2-170 (8)

aa83-112 (7)

N-Terminus (4)

aa63-112 (4)

aa25-75 (1)

Publications

No (40)

Tag

GST (1)

GST, N-terminus (2)

His (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Select

DR1 / NC2 Antibody LS-C755318

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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DR1 / NC2 Antibody LS-C816276

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$412

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DR1 / NC2 Antibody LS-C675659

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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DR1 / NC2 Antibody LS-C748353

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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DR1 / NC2 Antibody LS-C482721

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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DR1 / NC2 Antibody LS-C766159

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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DR1 / NC2 Antibody LS-C349290

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

DR1 / NC2 Antibody (aa83-112) LS-C320949

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa83-112) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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DR1 / NC2 Antibody (aa83-112, Biotin) LS-C256314

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa83-112) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

DR1 / NC2 Antibody (aa83-112, FITC) LS-C256315

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa83-112) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

DR1 / NC2 Antibody (aa83-112, APC) LS-C256312

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa83-112) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DR1 / NC2 Antibody (aa83-112, Azide-free, HRP) LS-C256316

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa83-112) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

DR1 / NC2 Antibody (aa83-112, PE) LS-C256317

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa83-112) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

DR1 / NC2 Antibody LS-C307885

Antibody:

DR1 / NC2 Mouse anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$705

Select

DR1 / NC2 Antibody (aa63-112) LS-C145911

Antibody:

DR1 / NC2 Rabbit anti-Mouse Polyclonal (aa63-112) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

DR1 / NC2 Antibody (aa63-112, HRP) LS-C426300

Antibody:

DR1 / NC2 Rabbit anti-Mouse Polyclonal (aa63-112) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

DR1 / NC2 Antibody (aa63-112, Biotin) LS-C426297

Antibody:

DR1 / NC2 Rabbit anti-Mouse Polyclonal (aa63-112) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

DR1 / NC2 Antibody (aa63-112, FITC) LS-C426298

Antibody:

DR1 / NC2 Rabbit anti-Mouse Polyclonal (aa63-112) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DR1 / NC2 Antibody (N-Terminus) LS-C30584

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

DR1 / NC2 Antibody (N-Terminus, HRP) LS-C436418

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

DR1 / NC2 Antibody (N-Terminus, Biotin) LS-C436416

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

DR1 / NC2 Antibody (N-Terminus, FITC) LS-C436417

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DR1 / NC2 Antibody (aa25-75) LS-C288644

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa25-75) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

DR1 / NC2 Antibody (aa2-170) LS-C314729

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa2-170) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182

Select

DR1 / NC2 Antibody (aa83-112) LS-C159487

Antibody:

DR1 / NC2 Rabbit anti-Human Polyclonal (aa83-112) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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