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DPYSL2 / CRMP2
dihydropyrimidinase-like 2
DPYSL2 / CRMP2 is a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
| Gene Name: | dihydropyrimidinase-like 2 |
| Synonyms: | DPYSL2, CRMP2, CRMP-2, DHPRP2, Dihydropyrimidinase-like 2, DRP-2, N2A3, ULIP2, ULIP-2, Unc-33-like phosphoprotein 2 |
| Target Sequences: | NM_001386 NP_001377.1 Q16555 |
Publications (4)
1
Glyoxalase 1-knockdown in human aortic endothelial cells - effect on the proteome and endothelial function estimates. Stratmann B, Engelbrecht B, Espelage BC, Klusmeier N, Tiemann J, Gawlowski T, Mattern Y, Eisenacher M, Meyer HE, Rabbani N, Thornalley PJ, Tschoepe D, Poschmann G, Stühler K. Scientific reports. 2016 6:37737. (WB; Human)
[Full Text Article]
[PubMed:27898103]
[PMC:PMC5127188]
Related Antibodies: LS-B3616.
2
Discovery of new membrane-associated proteins overexpressed in small-cell lung cancer. Sebahat Ocak, David B Friedman, Heidi Chen, Jamie A Ausborn, Mohamed Hassanein, Bruno Detry, Birgit Weynand, Frank Aboubakar, Charles Pilette, Yves Sibille, Pierre P Massion. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014 March;9:324-36. [Full Text Article]
[PubMed:24518087]
[PMC:PMC4028683]
Related Antibodies: LS-C198892.
3
The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and axonal extension after spinal cord injury. Kazumichi Yagura, Hirokazu Ohtaki, Tomomi Tsumuraya, Atsushi Sato, Kazuyuki Miyamoto, Naoto Kawada, Keisuke Suzuki, Motoyasu Nakamura, Koji Kanzaki, Kenji Dohi, Masahiko Izumizaki, Yutaka Hiraizumi, Kazuho Honda. PloS one. 2020 Mar;15:e0230080. [Full Text Article]
[PubMed:32155215]
[PMC:PMC7064230]
Related Antibodies: LS-B5657.
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DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (aa480-529) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
DPYSL2 / CRMP2 Mouse anti-Human Monoclonal (aa463-492) (33CT11.40.3) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
![DPYSL2 / CRMP2 Antibody - Immunofluorescence of monoclonal antibody to DPYSL2 on HeLa cell . [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/dpysl2-crmp2-antibody-clone-1f11-ls-c197078/144604_5056127.jpg)
DPYSL2 / CRMP2 Mouse anti-Human Monoclonal (1F11) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
Yeast
6His, N-terminus
64.3 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
DPYSL2 / CRMP2 Rabbit anti-Human Monoclonal (C-Terminus) (EPR7792) Antibody
Mouse, Rat, Human
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (pThr514) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (pThr514) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (aa475-524) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (aa461-510) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (pThr514) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (p514) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (pThr514) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (450-530 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (450-530 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IP, WB
Unconjugated
100 µl/$412
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (Pro510) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
DPYSL2 / CRMP2 Rabbit anti-Human Polyclonal (pThr509) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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