Human DPP4 / CD26
DPP4 | ADCP-2 | ADABP | Dipeptidyl peptidase IV | Dipeptidyl-peptidase 4 | DPPIV | ADCP2 | T-cell activation antigen CD26 | CD26 | CD26 antigen | Dipeptidyl peptidase 4 | Dipeptidylpeptidase 4 | DPP IV | TP103
(tested or 100% immunogen sequence identity)
Also available Unconjugated
Human T-cell leukaemia cells (T-CLL)
Recognizes human Dipeptidyl peptidase 4, also known as Adenosine deaminase complexing protein 2, CD26, TP103, ADABP or DPP IV. CD26 is a 766 amino acid ~110 kD single pass type II transmembrane glycoprotein expressed by activated T cells, B cells and macrophages. A soluble form of CD26 can be derived by cleavage of the membrane bound form between residues 38-39. CD26 acts as a functional receptor for the pathogenic Middle East respiratory syndrome coronavirus [MERS-CoV], a severe and frequently fatal disease in humans and marmosets sharing identical CD26 sequence at the site of interaction with the MERS-CoV spike protein. Has been used successfully for the immunohistochemical detection of CD26 on formalin fixed, paraffin embedded tissues and the demonstration of elevated CD26 expression in thyroid neoplasia. Has also been used for the immunohistochemical detection of CD26 on cryostat sections using both immunoperoxidase and immunofluorescence staining in liver biopsies from NASH patients.