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DOT1L / DOT1

DOT1-like histone H3K79 methyltransferase

Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

Gene Name: DOT1-like histone H3K79 methyltransferase
Synonyms: DOT1L, DOT1, DOT1-like protein, KMT4, Lysine N-methyltransferase 4, KIAA1814, H3-K79-HMTase
Target Sequences: AK055359 NP_115871.1 Q8TEK3

☰ Filters
Antibodies (44)
Proteins (4)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (44)
Recombinant (2)
Sandwich (2)
DOT1L / DOT1 (50)
Human (45)
Mouse (6)
Rat (4)
IHC (17)
IHC-P (5)
WB (32)
ChIP-Seq (1)
ELISA (12)
IP (3)
Peptide-ELISA (1)
rabbit (20)
mouse (24)
Product Group
IHCPlus (2)
IgG (18)
IgG1 (20)
IgG1,k (1)
IgG2a (1)
IgG2b (2)
monoclonal mc (24)
polyclonal pc (20)
1F1D4 (2)
8B2 (1)
OTI11H2 (2)
OTI1D8 (2)
OTI1F6 (2)
OTI1F8 (2)
OTI2B10 (2)
OTI3E9 (2)
OTI5D12 (2)
OTI6E7 (2)
OTI7H6 (2)
OTI8A11 (2)
TS106 (1)
96-Well Microplate (1)
96-Well Strip Plate (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
Carrier-free (11)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (36)
aa1008-1424 (12)
aa1-434 (10)
C-Terminus (6)
aa1000-1050 (2)
aa1485-C-term (1)
aa2-416 (1)
No (50)
Cell Lysates (2)
Tissue Homogenates (2)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
DOT1L / DOT1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1008-1424) (1F1D4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DOT1L / DOT1 Antibody - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DOT1L / DOT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
DOT1L / DOT1 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer at dilution of 1:100
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DOT1L / DOT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
DOT1L / DOT1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$902
DOT1L / DOT1 Antibody - Detection of Human DOT1L by Immunohistochemistry. Sample: FFPE section of human lung carcinoma. Antibody: Affinity purified rabbit anti-DOT1L used at a dilution of 1:200 (1 Detection: DAB.
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DOT1L / DOT1 Rabbit anti-Human Polyclonal (aa1000-1050) Antibody
Human
ChIP-Seq, IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
DOT1L / DOT1 Antibody - IHC of paraffin-embedded Human thyroid tissue using anti-DOT1L mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1008-1424) (OTI6E7) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DOT1L / DOT1 Antibody - IHC of paraffin-embedded Human thyroid tissue using anti-DOT1L mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1008-1424) (Carrier-free) (OTI6E7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DOT1L / DOT1 Antibody - IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-DOT1L mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1-434) (OTI1D8) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
DOT1L / DOT1 Antibody - IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-DOT1L mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1-434) (Carrier-free) (OTI1D8) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
DOT1L / DOT1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1008-1424) (Carrier-free) (1F1D4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal (C-Terminus) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal (C-Terminus) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal (C-Terminus) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa2-416) (TS106) Antibody
Human
IHC, IP
Unconjugated
100 µg/$884
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (8B2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
DOT1L / DOT1 Antibody - Western blot analysis of DOT1L expression in HEK293 cells. The lane on the left is treated with the antigen-specific peptide.
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DOT1L / DOT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DOT1L / DOT1 Antibody - Detection of Human DOT1L by Immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-DOT1L used at a dilution of 1:100. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.
Select
DOT1L / DOT1 Rabbit anti-Human Polyclonal (aa1000-1050) Antibody
Human
IHC
Unconjugated
1 µg/$295; 100 µl/$532
DOT1L / DOT1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DOT1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DOT1L.
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1-434) (OTI1F8) Antibody
Human
WB
Unconjugated
100 µl/$434
DOT1L / DOT1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DOT1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DOT1L.
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1008-1424) (OTI8A11) Antibody
Human
WB
Unconjugated
100 µl/$434
DOT1L / DOT1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DOT1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DOT1L.
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1008-1424) (OTI3E9) Antibody
Human
WB
Unconjugated
100 µl/$434
DOT1L / DOT1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DOT1L (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DOT1L.
Select
DOT1L / DOT1 Mouse anti-Human Monoclonal (aa1008-1424) (OTI11H2) Antibody
Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 50 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).