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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DNMT3L Antibody (Biotin)

DNMT3L antibody LS-C502108 is a biotin-conjugated rabbit polyclonal antibody to human DNMT3L. Validated for ELISA.
Catalog
Size
Price
LS-C502108-50
50 µg
$285
LS-C502108-100
100 µg
$385
Description
DNMT3L antibody LS-C502108 is a biotin-conjugated rabbit polyclonal antibody to human DNMT3L. Validated for ELISA.
Target
Human DNMT3L
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA
  • (applications tested for the base form of this product only)
Immunogen
DNMT3L antibody was raised against recombinant Human DNA (cytosine-5)-methyltransferase 3-like protein (1-234AA)
Specificity
Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only.
About DNMT3L
Q9UJW3 NM_013369 NP_037501.2

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Requested From: United States
Date Requested: 1/23/2019
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