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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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DNM1 / Dynamin Antibody (phospho‑Ser774) LS‑C241

Catalog Number Size Price
LS-C241-100 100 µl $375 
Western blot of rat hippocampal lysate stimulated with forskolin showing specific immunolabeling of the ~95k dynamin phosphorylated at Ser774 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: l-Ptase). The blot is identical to the control except that it was incubated in ll-Ptase (1200 units for 30 min) before being exposed to the Anti-Ser774 dynamin. The immunolabeling is completely eliminated by treatment with l-Ptase.

DNM1 / Dynamin Antibody (phospho‑Ser774) LS‑C241

Note: This antibody replaces LS-C22965
Antibody:
Sheep Polyclonal to Rat DNM1 / Dynamin
Application:
IHC, WB
Reactivity:
Rat, Human, Mouse, Bovine, Dog, Chicken
Format:
Unconjugated, Unmodified
Price
Catalog Number
$375 
LS-C241-100
Toll Free North America
866-819-4732

Overview

Antibody:
Sheep Polyclonal to Rat DNM1 / Dynamin
Application:
IHC, WB
Reactivity:
Rat, Human, Mouse, Bovine, Dog, Chicken
Format:
Unconjugated, Unmodified

Specifications

Description
Dynamin antibody LS-C241 is an unconjugated sheep polyclonal antibody to Dynamin (DNM1 ) from human, mouse, rat and other species. Validated for IHC and WB.
Target
Rat DNM1 / Dynamin
Host
Sheep
Reactivity
Rat, Human, Mouse, Bovine, Dog, Chicken (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:1000)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Phosphopeptide corresponding to amino acid residues surrounding the phospho Ser774 of rat dynamin.
Epitope
pSer774
Specificity
Specific for the ~95k dynamin protein phosphorylated at Ser774. Labels the purified protein phosphorylated in vitro by cdk5 but not by PKC. Does not cross react with other purified substrates of cdk5 (e. g. amphiphysin and synapsin). Immunolabeling is blocked by X-phosphatase treatment.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/mL BSA, 50% Glycerol
Storage
Short term: -20°C; Long term: -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About DNM1 / Dynamin
Q05193 NM_004408 NP_004399.2

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Western blot of rat hippocampal lysate stimulated with forskolin showing specific immunolabeling of the ~95k dynamin phosphorylated at Ser778 (Control). The phosphospecificity of this labeling is shown in the second lane (lambda-phosphatase: lambda phosph
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Requested From: United States
Date Requested: 8/25/2019
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