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DNASE2 / DNase II

deoxyribonuclease II, lysosomal

Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Gene Name: deoxyribonuclease II, lysosomal
Family/Subfamily: DNase
Synonyms: DNASE2, Acid DNase, DNase II, DNase II alpha, DNASE2A, Deoxyribonuclease II alpha, Deoxyribonuclease-2-alpha, DNase II, lysosomal, R31240_2, DNL, DNL2, Lysosomal DNase II
Target Sequences: NM_001375 NP_001366.1 O00115

☰ Filters
Antibodies (27)
Proteins (7)
ELISA Kits (1)
Over-Expression Lysate (2)
Primary (27)
Recombinant (5)
Sandwich (1)
DNASE2 / DNase II (35)
Human (26)
Mouse (3)
Rat (1)
IHC (2)
IHC-P (3)
WB (20)
ELISA (8)
ICC (2)
IF (3)
IP (2)
Peptide-ELISA (1)
rabbit (26)
mouse (1)
Product Group
IHCPlus (2)
IgG (19)
polyclonal pc (27)
96-Well Microplate (1)
APC (1)
APC Conjugated (2)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (12)
aa19-360 (8)
C-Terminus (3)
No (35)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
GST (2)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (2)
DNASE2 / DNase II Antibody - Anti-DNASE2 / DNase II antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$545
Select
DNASE2 / DNase II Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA
Unconjugated
100 µg/$832
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
DNASE2 / DNase II Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA
Unconjugated
100 µl/$801
DNASE2 / DNase II Antibody - Human Pancreas, Adipocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (aa19-360) Antibody
Human
ICC, IHC-P, IP, WB
Unconjugated
50 µl/$460
DNASE2 / DNase II Protein - Recombinant  Deoxyribonuclease II By SDS-PAGE
Select
E. coli
His-T7
41.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
DNASE2 / DNase II Antibody - Immunofluorescence staining of DNASE2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human DNASE2 polyclonal antibody (dilution ratio 1:500) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm.
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
20 µl/$271; 100 µl/$412
DNASE2 / DNase II Antibody - Immunohistochemistry of human spleen with Rabbit anti-DNASE-II
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$434
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
DNASE2 / DNase II Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
DNASE2 / DNase II Antibody - IHC image of DNASE2 Antibody diluted at 1:400 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
DNASE2 / DNase II Antibody - Western blot of DNASE2 / DNase II antibody.
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (aa19-360) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
DNASE2 / DNase II Antibody - Western blot of DNASE2 / DNase II antibody.
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (aa19-360) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
DNASE2 / DNase II Antibody - Western blot of DNASE2 / DNase II antibody.
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (aa19-360) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
DNASE2 / DNase II Antibody - Western blot of DNASE2 / DNase II antibody.
Select
DNASE2 / DNase II Rabbit anti-Human Polyclonal (aa19-360) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Viewing 1-25 of 35 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).