Human DNAM-1 / CD226

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

DX11

Unconjugated. Also available conjugated with RPE, Biotin, FITC.

Protein G purified

Unmodified. Also available Low Endotoxin.

Human cytotoxic T lymphocyte clone

Recognizes human CD226, a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells. XXX recommend the use of MCA2257XZ for functional studies.

• Immunoprecipitation
• Flow Cytometry (1:25 - 1:100)

Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q15762 NCBI: NM_006566 NP_006557.2