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DNAJA1 / HDJ2

DnaJ (Hsp40) homolog, subfamily A, member 1

Co-chaperone for HSPA8/Hsc70 (PubMed:10816573). Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202).

Gene Name: DnaJ (Hsp40) homolog, subfamily A, member 1
Synonyms: DNAJA1, DNAJ2, HDJ-2, HDJ2, HSJ2, HSPF4, Human DnaJ protein 2, NEDD7, HSDJ, DJ-2, DjA1, DnaJ protein homolog 2, Heat shock 40 kDa protein 4, Heat shock protein J2, HSJ-2
Target Sequences: NM_001539 NP_001530.1 P31689

Publications (1)

1
The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity. Julia Ring , Jelena Tadic , Selena Ristic, Michael Poglitsch, Martina Bergmann, Nemanja Radic, Dirk Mossmann, YongTian Liang, Marta Maglione, Andrea Jerkovic, Roozbeh Hajiraissi, Marcel Hanke, Victoria Küttner, Heimo Wolinski, Andreas Zimmermann, Lana Domuz Trifunovic, Leonie Mikolasch, Daiana N Moretti, Filomena Broeskamp, Julia Westermayer, Claudia Abraham, Simon Schauer, Christopher Dammbrueck, Sebastian J Hofer, Mahmoud Abdellatif, Guido Grundmeier, Guido Kroemer, Ralf J Braun, Niklas Hansen. EMBO molecular medicine. 2022 May;14:e13952. [Full Text Article] [PubMed:35373908] [PMC:PMC9081910]

☰ Filters
Antibodies (28)
Proteins (5)
Over-Expression Lysate (2)
Primary (28)
Recombinant (3)
DNAJA1 / HDJ2 (33)
Human (26)
Mouse (15)
Rat (13)
Bat (1)
Bovine (5)
Chimpanzee (3)
Dog (3)
E. coli (1)
Gibbon (3)
Guinea pig (4)
Hamster (4)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (4)
Rabbit (4)
Zebrafish (3)
IHC (12)
IHC-P (2)
WB (25)
Flo (7)
ELISA (14)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (28)
IgG (19)
polyclonal pc (28)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (17)
aa294-323 (7)
N-Terminus (4)
Internal (1)
aa250-300 (1)
aa369-384 (1)
aa379-414 (1)
No (33)
GST (1)
Myc-DDK (Flag) (3)
E. coli (1)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
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DNAJA1 / HDJ2 Rabbit anti-E. coli Polyclonal Antibody
E. coli
IP, WB
Unconjugated
50 µg/$582; 200 µg/$984
DNAJA1 / HDJ2 Antibody - Western blot of HSP40/Hdj2polyclonal antibody: Lane 1: MWM, Lane 2: Hsp40/Hdj2 Recombinant Human Protein, Lane 3: HeLa Cell Lysate, Lane 4: HeLa Cell Lysate, Heat Shocked, Lane 5: PC-12 Cell Lysate, Lane 6: PC-12 Cell Lysate, Heat Shocked, Lane 7: 3T3 Cell Lysate, Lane 8: 3T3 Cell Lysate, Heat Shocked, Lane 9: CHO-K1 Cell Lysate, Lane 10: CHO-K1 Cell Lysate, Heat Shocked.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Hamster, Human
WB
Unconjugated
200 µg/$543
DNAJA1 / HDJ2 Antibody - Immunohistochemistry Dilution at 1:1000 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
DNAJA1 / HDJ2 Antibody - DNAJA1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa294-323) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa294-323) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa294-323) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa294-323) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa294-323) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa294-323) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa294-323) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
DNAJA1 / HDJ2 Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DNAJA1 / HDJ2 Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using DNAJA1 Polyclonal Antibody at dilution of 1:60.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
DNAJA1 / HDJ2 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using DNAJA1 Polyclonal Antibody at dilution of 1:30.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
DNAJA1 / HDJ2 Antibody - Western blot analysis of lysate from mouse liver cells, using DNAJA1 Antibody.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
DNAJA1 / HDJ2 Antibody - DNAJA1 antibody Western blot of Mouse Liver lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DNAJA1 / HDJ2 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$424
DNAJA1 / HDJ2 Antibody - DNAJA1 antibody Western blot of Mouse Liver lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DNAJA1 / HDJ2 Rabbit anti-Mouse Polyclonal (N-Terminus) (HRP) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
DNAJA1 / HDJ2 Antibody - DNAJA1 antibody Western blot of Mouse Liver lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DNAJA1 / HDJ2 Rabbit anti-Mouse Polyclonal (N-Terminus) (Biotin) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
DNAJA1 / HDJ2 Antibody - DNAJA1 antibody Western blot of Mouse Liver lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DNAJA1 / HDJ2 Rabbit anti-Mouse Polyclonal (N-Terminus) (FITC) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$343; 120 µl/$427; 200 µl/$559
DNAJA1 / HDJ2 Antibody - Western blot of lysates from HepG2, SK-BR-3, Raji cell line, mouse lung tissue lysate and rat PC-12 cell line (from left to right) with DNAJA1 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35 ug per lane.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa379-414) Antibody
Mouse, Rat, Human
WB
Unconjugated
400 µl/$393
DNAJA1 / HDJ2 Antibody - Western blot analysis of extracts of various cell lines, using DNAJA1 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
DNAJA1 / HDJ2 Antibody - Detection of human and mouse DNAJA1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-DNAJA1 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa250-300) Antibody
Mouse, Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
DNAJA1 / HDJ2 Antibody - Western blot analysis of HDJ2 expression in HeLa (A); mouse liver (B); mouse brain (C) whole cell lysates.
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DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Human
WB
Unconjugated
100 µl/$321
DNAJA1 / HDJ2 Antibody - WB of DNAJA1 / HDJ2 antibody. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Lung Tissue Lysate. Lane 3: Mouse Brain Tissue Lysate. Lane 4: Mouse Lung Tissue Lysate. Lane 5: U87 Cell Lysate. Lane 6: A549 Cell Lysate. Lane 7: COLO320 Cell Lysate. Lane 8: A431 Cell Lysate. Lane 9: HT1080 Cell Lysate.
Select
DNAJA1 / HDJ2 Rabbit anti-Human Polyclonal (aa369-384) Antibody
Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 33 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).