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DMP1

dentin matrix acidic phosphoprotein 1

Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.

Gene Name: dentin matrix acidic phosphoprotein 1
Synonyms: DMP1, Dentin matrix protein 1, DMP-1, ARHP, ARHR
Target Sequences: NM_004407 NP_004398.1 Q13316

Publications (1)

1
Osteoblastic glucocorticoid signaling exacerbates high-fat-diet- induced bone loss and obesity. Sarah Kim , Holger Henneicke , Lauryn L Cavanagh, Eugenie Macfarlane, Lee Joanne Thai, Daphne Foong, Sylvia J Gasparini, Colette Fong-Yee, Michael M Swarbrick , Markus J Seibel , Hong Zhou. Bone research. 2021 Sep;9:40. [Full Text Article] [PubMed:34465731] [PMC:PMC8408138]

☰ Filters
Antibodies (25)
ELISA Kits (8)
Proteins (7)
Custom (2)
Primary (25)
Recombinant (7)
Sandwich (6)
DMP1 (40)
Human (27)
Mouse (5)
Rat (1)
Monkey (2)
IHC (1)
WB (19)
ELISA (21)
IF (1)
Peptide-ELISA (2)
rabbit (14)
mouse (9)
goat (1)
sheep (1)
IgG (11)
IgG1 (2)
IgG2b,k (7)
monoclonal mc (10)
polyclonal pc (15)
001 (1)
11D61 (1)
1D4 (1)
96-Well Microplate (2)
96-Well Strip Plate (6)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Preservative Free (2)
Unconjugated (14)
aa146-175 (7)
aa221-331 (1)
aa228-239 (1)
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6His, C-terminus (2)
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Myc-DDK (Flag) (1)
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HEK 293 Cells (1)
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Purified (3)
Low endotoxin level (3)
Select
DMP1 Sheep anti-Mouse Polyclonal Antibody
Mouse
ELISA, IHC, WB
Unconjugated
100 µg/$930
Select
DMP1 Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
DMP1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
DMP1 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$795
DMP1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
163.8 - 16000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
DMP1 Antibody - Immunofluorescence of monoclonal antibody to DMP1 on HeLa cell . [antibody concentration 10 ug/ml]
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DMP1 Mouse anti-Human Monoclonal (1D4) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
Select
DMP1 Mouse anti-Human Monoclonal (aa221-331) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
DMP1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
DMP1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
DMP1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
DMP1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
DMP1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
DMP1 Rabbit anti-Human Polyclonal (aa146-175) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
DMP1 Rabbit anti-Human Polyclonal (aa146-175) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
DMP1 Rabbit anti-Human Polyclonal (aa146-175) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
DMP1 Rabbit anti-Human Polyclonal (aa146-175) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
DMP1 Rabbit anti-Human Polyclonal (aa146-175) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
DMP1 Rabbit anti-Human Polyclonal (aa146-175) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
DMP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
DMP1 Antibody - Western blot analysis of DMP1 using COS7 whole cells lysates
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DMP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DMP1 Antibody - Antibody (1 ug/ml) staining of Human Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
Select
DMP1 Goat anti-Human Polyclonal (aa228-239) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
Select
DMP1 Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
500 µg/$1,079
Select
DMP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
DMP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$382
Select
DMP1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
Viewing 1-25 of 40 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).