DLAT / PDC-E2

dihydrolipoamide S-acetyltransferase

DLAT / PDC-E2 is component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.

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Products

Antibodies (53)

ELISA Kits (13)

Proteins (9)

Type

Competitive EIA (1)

Over-Expression Lysate (2)

Primary (53)

Recombinant (7)

Sandwich (11)

Sandwich CLIA (1)

Target

DLAT / PDC-E2 (75)

Reactivity

Human (54)

Mouse (26)

Rat (14)

Bat (3)

Bovine (6)

Chicken (1)

Chimpanzee (3)

Dog (6)

Gibbon (6)

Guinea pig (7)

Hamster (6)

Horse (6)

Monkey (7)

Pig (6)

Porcine (1)

Rabbit (9)

Sheep (1)

Zebrafish (3)

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Application

IHC (14)

IHC-P (7)

WB (50)

Flo (7)

ELISA (9)

ICC (2)

IF (6)

IP (3)

Host

rabbit (49)

mouse (4)

Product Group

IHCPlus (1)

Isotype

IgG (32)

Clonality

monoclonal mc (3)

polyclonal pc (50)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (1)

96-Well Strip Plate (10)

APC (2)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (7)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (4)

Preservative Free (1)

Unconjugated (20)

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Epitope

aa368-626 (8)

aa374-631 (8)

aa579-607 (7)

aa540-589 (4)

aa61-110 (4)

Publications

No (75)

Sample Type

Cell Lysates (1)

Plasma (6)

Serum (6)

Tissue Homogenates (2)

Tag

6His, N-terminus (3)

GST (1)

His, N-Terminal (2)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (3)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (5)

Select

Mouse DLAT / PDC-E2 Protein (Recombinant 6His, N-terminus) (aa86-642) - LS-G57328

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Mouse DLAT / PDC-E2 Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G136485

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

62.8 kDa

Price:

20 µg/$405; 1 mg/$1,679; 100 µg/$598

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Mouse DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F21360

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human DLAT / PDC-E2 Protein (Recombinant 6His, N-terminus) (aa93-640) - LS-G56220

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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DLAT / PDC-E2 Antibody (aa579-607) LS-C320853

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa579-607) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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DLAT / PDC-E2 Antibody (aa579-607, Biotin) LS-C222112

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa579-607) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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DLAT / PDC-E2 Antibody (aa579-607, FITC) LS-C222113

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa579-607) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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DLAT / PDC-E2 Antibody (aa579-607, APC) LS-C222111

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa579-607) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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DLAT / PDC-E2 Antibody (aa579-607, Azide-free, HRP) LS-C222115

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa579-607) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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DLAT / PDC-E2 Antibody (aa579-607, PE) LS-C222116

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa579-607) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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Mouse DLAT / PDC-E2 Protein (Recombinant His, N-Terminal) (Thr368-Trp626) - LS-G12649

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

29.0 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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IHC-plus™ DLAT / PDC-E2 Antibody LS-B16939

(4.0) Rating

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

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Mouse DLAT / PDC-E2 (Sandwich ELISA) ELISA Kit - LS-F5272

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$782

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DLAT / PDC-E2 Antibody LS-C393578

Antibody:

DLAT / PDC-E2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Human

Applications:

ICC, IP, WB

Format:

Unconjugated

Price:

100 µl/$391

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DLAT / PDC-E2 Antibody LS-C670013

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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DLAT / PDC-E2 Antibody (aa368-626) LS-C293685

Antibody:

DLAT / PDC-E2 Rabbit anti-Mouse Polyclonal (aa368-626) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161

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DLAT / PDC-E2 Antibody (aa368-626, Biotin) LS-C301003

Antibody:

DLAT / PDC-E2 Rabbit anti-Mouse Polyclonal (aa368-626) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$311; 200 µl/$353; 500 µl/$496; 1 ml/$567; 2 ml/$769; 5 ml/$1,248

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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DLAT / PDC-E2 Antibody (aa579-607) LS-C167430

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa579-607) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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DLAT / PDC-E2 Antibody (aa540-589, FITC) LS-C443070

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal (aa540-589) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

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DLAT / PDC-E2 Antibody LS-C833322

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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Mouse DLAT / PDC-E2 (CLIA) ELISA Kit - LS-F30639

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human DLAT / PDC-E2 Protein (Recombinant His, N-Terminal) (Gln374-Trp631) - LS-G12650

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

28.7 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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DLAT / PDC-E2 Antibody LS-C334616

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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DLAT / PDC-E2 Antibody LS-C482553

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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DLAT / PDC-E2 Antibody LS-C766087

Antibody:

DLAT / PDC-E2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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