DKK2

dickkopf WNT signaling pathway inhibitor 2

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

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Products

Antibodies (42)

ELISA Kits (19)

Proteins (8)

Type

Competitive EIA (2)

Over-Expression Lysate (2)

Primary (42)

Recombinant (6)

Sandwich (15)

Sandwich CLIA (2)

Target

DKK2 (69)

Reactivity

Human (48)

Mouse (15)

Rat (9)

Bat (4)

Bovine (1)

Chicken (1)

Dog (4)

Gibbon (3)

Guinea pig (4)

Horse (4)

Monkey (5)

Pig (4)

Porcine (1)

Rabbit (4)

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Application

IHC (20)

IHC-P (6)

WB (37)

ELISA (20)

Peptide-ELISA (2)

Host

rabbit (40)

mouse (1)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (24)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (41)

Clone

1833CT856.7.20 (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (3)

96-Well Strip Plate (14)

APC (1)

APC Conjugated (3)

Azide-free (2)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Unconjugated (19)

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Epitope

aa159-258 (8)

aa225-251 (7)

aa31-62 (7)

aa34-259 (5)

aa124-173 (4)

Asn70 (1)

Gly44 (1)

aa245-259 (1)

Publications

No (68)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (2)

Plasma (14)

Serum (14)

Tissue Homogenates (5)

Tag

Fc, N-terminus (1)

Fc, N-terminus + 6His, C-terminus (1)

His (2)

His-SUMO (1)

Myc-DDK (Flag) (2)

Species

Human (7)

Source

293T Cells (1)

CHO Cells (1)

E. coli (3)

HEK 293 Cells (1)

Human Cells (1)

Mammalian Cells (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (1)

Select

DKK2 Antibody (aa124-173) LS-B8226

Antibody:

DKK2 Rabbit anti-Mouse Polyclonal (aa124-173) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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DKK2 Antibody (aa124-173, Biotin) LS-C459585

Antibody:

DKK2 Rabbit anti-Mouse Polyclonal (aa124-173) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

Mouse DKK2 (Sandwich ELISA) ELISA Kit - LS-F24163

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

7.813 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human DKK2 (Sandwich ELISA) ELISA Kit - LS-F4401

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$798

Select

IHC-plus™ DKK2 Antibody (aa31-62) LS-B11830

(4.0) Rating

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa31-62) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

Select

Mouse DKK2 (Sandwich ELISA) ELISA Kit - LS-F13151

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

DKK2 Antibody (aa225-251) LS-C98294

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa225-251) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

DKK2 Antibody (clone 1833CT856.7.20) LS-C757933

Antibody:

DKK2 Mouse anti-Human Monoclonal (1833CT856.7.20) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

DKK2 Antibody (aa34-259, Biotin) LS-C370684

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa34-259) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

Rat DKK2 (Sandwich ELISA) ELISA Kit - LS-F24302

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 U/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human DKK2 Protein (Recombinant) - LS-G133788

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

25.8 kDa or 31-36 kDa

Price:

10 µg/$349; 2 µg/$268

Select

DKK2 Antibody (aa225-251) LS-C327202

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa225-251) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

DKK2 Antibody (aa225-251, Biotin) LS-C276794

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa225-251) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

DKK2 Antibody (aa225-251, FITC) LS-C276795

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa225-251) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

DKK2 Antibody (aa225-251, APC) LS-C276793

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa225-251) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DKK2 Antibody (aa225-251, Azide-free, HRP) LS-C276797

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa225-251) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

DKK2 Antibody (aa225-251, PE) LS-C276798

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa225-251) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

DKK2 Antibody (aa31-62) LS-C330408

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa31-62) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

DKK2 Antibody (aa31-62, Biotin) LS-C276788

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa31-62) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

DKK2 Antibody (aa31-62, FITC) LS-C276789

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa31-62) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

DKK2 Antibody (aa31-62, Azide-free, HRP) LS-C276790

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa31-62) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

DKK2 Antibody (aa31-62, APC) LS-C276787

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa31-62) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

DKK2 Antibody (aa31-62, PE) LS-C276791

Antibody:

DKK2 Rabbit anti-Human Polyclonal (aa31-62) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

DKK2 Antibody LS-C665098

Antibody:

DKK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

DKK2 Antibody LS-C400711

Antibody:

DKK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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