DKK1

dickkopf WNT signaling pathway inhibitor 1

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

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Products

Antibodies (95)

ELISA Kits (29)

Proteins (21)

Type

Competitive EIA (2)

Custom (1)

Over-Expression Lysate (2)

Primary (95)

Recombinant (19)

Sandwich (24)

Sandwich CLIA (2)

Target

DKK1 (145)

Reactivity

Human (93)

Mouse (33)

Rat (25)

Bat (7)

Bovine (7)

Chicken (4)

Chimpanzee (6)

Dog (7)

Gibbon (6)

Goat (4)

Guinea pig (6)

Horse (9)

Monkey (11)

Orangutan (3)

Pig (17)

Porcine (1)

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Rhesus monkey (3)

Xenopus (3)

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Application

IHC (9)

IHC-P (7)

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ELISA (29)

IF (1)

Neut (1)

Peptide-ELISA (2)

Host

rabbit (76)

mouse (17)

goat (1)

sheep (1)

Product Group

IHCPlus (5)

Isotype

IgG (35)

IgG1 (2)

IgG2b (3)

IgG2b,k (10)

Clonality

monoclonal mc (18)

polyclonal pc (77)

Clone

08 (1)

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2H2 (2)

R015 (1)

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (8)

96-Well Strip Plate (18)

AP Conjugated (1)

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Atto 594 Conjugated (1)

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aa33-266 (8)

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aa58-84 (7)

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Gln75 (1)

Internal (1)

Internal Region (1)

Ser140 (1)

aa150-200 (1)

aa250-262 (1)

aa68-83 (1)

aa71-266 (1)

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Publications

No (141)

Yes (4)

Sample Type

Cell Culture Supernatants (9)

Cell Lysates (3)

Plasma (26)

Serum (26)

Tissue Homogenates (6)

Tag

6His, C-terminus (1)

6His, N-terminus (2)

8His, N-terminus (1)

AVI-6His, C-terminus (1)

DDK,C-terminus (1)

Fc, C-terminus (1)

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Human (17)

Mouse (1)

Rat (1)

Source

293T Cells (1)

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CHO Cells (1)

E. coli (7)

HEK 293 Cells (4)

Human (2)

Human Cells (1)

Mammalian Cells (1)

Sf9 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (7)

Low Endotoxin Level

Low endotoxin level (9)

Biologically Active

Biologically active (3)

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IHC-plus™ DKK1 Antibody (Internal Region) LS-A2867

Fast Shipping

(5.0) Rating

(3) Publication(s)

Antibody:

DKK1 Rabbit anti-Human Polyclonal (Internal Region) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ DKK1 Antibody (aa250-262) LS-B194

(5.0) Rating

(2) Publication(s)

Antibody:

DKK1 Goat anti-Human Polyclonal (aa250-262) Antibody

Reactivity:

Mouse, Goat, Dog, Bovine, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ DKK1 Antibody (N-Terminus) LS-A2865

Fast Shipping

(4.0) Rating

Antibody:

DKK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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DKK1 Antibody LS-C331011

Antibody:

DKK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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DKK1 Antibody (C-Terminus) LS-C201644

(4.0) Rating

(1) Publication(s)

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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DKK1 Antibody (C-Terminus, FITC) LS-C459589

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Orangutan, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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Mouse DKK1 (Sandwich ELISA) ELISA Kit - LS-F10347

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$612

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DKK1 Antibody (aa150-200) LS-C47394

(4.0) Rating

(1) Publication(s)

Antibody:

DKK1 Rabbit anti-Human Polyclonal (aa150-200) Antibody

Reactivity:

Rabbit, Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$386

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IHC-plus™ DKK1 Antibody (N-Terminus) LS-A2866

Fast Shipping

(4.0) Rating

Antibody:

DKK1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ DKK1 Antibody (Internal) LS-A2868

Fast Shipping

(4.0) Rating

Antibody:

DKK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Pig, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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Human DKK1 Protein (Recombinant 6His, N-terminus) (aa33-266) - LS-G64227

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse DKK1 (Sandwich ELISA) ELISA Kit - LS-F2762

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

46.9 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

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DKK1 Antibody (clone 2A5) LS-C105117

Antibody:

DKK1 Mouse anti-Human Monoclonal (2A5) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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DKK1 Antibody (clone 2H2) LS-C108793

Antibody:

DKK1 Mouse anti-Human Monoclonal (2H2) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$403

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DKK1 Antibody (Biotin) LS-C684974

Antibody:

DKK1 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$314; 200 µl/$359; 500 µl/$506; 1 ml/$580; 2 ml/$797; 5 ml/$1,295

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DKK1 Antibody LS-C64746

Antibody:

DKK1 Sheep anti-Rat Polyclonal Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$930

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DKK1 Antibody (C-Terminus) LS-C6401

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$553; 100 µg/$820

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DKK1 Antibody (C-Terminus) LS-C81144

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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DKK1 Antibody (C-Terminus, HRP) LS-C450638

Antibody:

DKK1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Xenopus, Zebrafish, Pig, Horse, Rabbit, Goat, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP

• Unconjugated
• HRP

Select

DKK1 Antibody (aa71-266) LS-C332169

Antibody:

DKK1 Rabbit anti-Human Polyclonal (aa71-266) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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DKK1 Antibody LS-C665096

Antibody:

DKK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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DKK1 Antibody (clone R015, Preservative Free) LS-C820652

Antibody:

DKK1 Rabbit anti-Human Monoclonal (Preservative Free) (R015) Antibody

Reactivity:

Human

Applications:

Neut

Format:

Unconjugated, Preservative Free

Price:

200 µg/$398; 500 µg/$511

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Porcine DKK1 (Sandwich ELISA) ELISA Kit - LS-F43278

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human DKK1 (Sandwich ELISA) ELISA Kit - LS-F4835

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$764

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Human DKK1 Protein (Recombinant) - LS-G105

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

35-40 kDa

Price:

2 µg/$268; 10 µg/$349

Viewing 1-25 of 145 product results

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