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Catalog Number Size Price
LS-C744094-100 100 µg $856 
Antibody

Polyclonal Rabbit anti‑Human DEFB4A / BD‑2 Antibody LS‑C744094

Polyclonal Rabbit anti‑Human DEFB4A / BD‑2 Antibody LS‑C744094

Antibody:
DEFB4A / BD-2 Rabbit anti-Human Polyclonal Antibody
Application:
ELISA, RIA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$856
LS-C744094-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
DEFB4A / BD-2 Rabbit anti-Human Polyclonal Antibody
Application:
ELISA, RIA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
BD-2 antibody LS-C744094 is an unconjugated rabbit polyclonal antibody to BD-2 (DEFB4A) from human. It is reactive with human, mouse and rat. Validated for ELISA and RIA.
Target
Human DEFB4A / BD-2
Synonyms
DEFB4A | Beta-defensin 2 | Beta-defensin 4A | DEFB-2 | DEFB102 | Defensin, beta 2 | Defensin, beta 4 | Defensin, beta 4A | DEFB4 | DEFB2 | HBD-2 | Skin-antimicrobial peptide 1 | BD-2 | SAP1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Mixture of synthetic peptides (14 AA near N-Terminus of mature HBD-2, 14 AA near N-Terminus of mature rat ß-Defensin-2, and 17 AA near N-Terminus of mature mouse ß-Defensin-2) coupled to KLH for immunisation of rabbits
Applications
  • ELISA (0.5 - 1 µg/ml)
  • Radioimmunoassay
Usage
Human defensins are Cys-rich antimicrobial peptides which specifically react against Gram-negative bacteria. Originally defensins were isolated from hemolysates, but they can also be found on the cell surface of epithelia of the urogenital tract, lung, and trachea. In leukocytes defensins are stored in granules being released into phagolysosomes for the destruction of incorporated microorganisms. Amino acid sequences of alpha-defensins 1-4 (HNP1-4) and beta-Defensins 1-4 (HBD1-4) are known. Beta-defensin-1 and beta-defensin-2 share 34% amino acid sequence homology. ß-defensin-2 (HBD-2) whole molecule and N-terminal fragments of HBD-2, no cross-reactivity to alpha-defensin and other beta-defensins, full cross-reaction with mouse and rat beta-defensin-2.
Presentation
PBS, BSA
Reconstitution
Reconstitute with 0.1 ml distilled H2O.
Storage
Store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About DEFB4A / BD-2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 1/25/2022