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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-C96234-100 100 µg $605 
DEF / Defensin Antibody - IHC of DEF / Defensin antibody. Frozen section of human umbilical cord.
DEF / Defensin Antibody - IHC of DEF / Defensin antibody. Frozen section of human umbilical cord.
DEF / Defensin Antibody - IHC of DEF / Defensin antibody. Formalin-fixed, paraffin-embedded human tonsil.
DEF / Defensin Antibody - IHC of DEF / Defensin antibody. Frozen section of human umbilical cord.
DEF / Defensin Antibody - IHC of DEF / Defensin antibody. Frozen section of human umbilical cord.
DEF / Defensin Antibody - IHC of DEF / Defensin antibody. Formalin-fixed, paraffin-embedded human tonsil.
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DEF / Defensin Antibody (clone Def‑3) LS‑C96234

DEF / Defensin Antibody (clone Def‑3) LS‑C96234

Antibody:
Mouse Monoclonal to DEF / Defensin
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$605 
LS-C96234-100
100 µg
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to DEF / Defensin
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Defensin antibody LS-C96234 is an unconjugated mouse monoclonal antibody to human Defensin (DEF ). Validated for IHC.
Target
DEF / Defensin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Monoclonal
Clone
Def-3
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Native defensins
Specificity
Several defensins are recognized, the epitope has not been further characterized. Biological functions: Various functions have been described for defensins. They are antibacterial, antifungal, chemotactic for monocytes, inhibitory for ACTH-induced corticosteroid synthesis and cytotoxic for cells. Defensins are inhibited by glucosaminoglycans (self protection for cells) and high concentrations of Calpha 2+ ions. Biochemistry: Defensins are a group of cyclic peptides containing 29-35 amino acids (MW < 3500) which tend to form aggregates. The molecules are protease resistant. The defensin content of azurophilic granules in neutrophils is approximately 30% of the total protein. Specificity: Human: Defensin 1-3 (HNP-1 to HNP-3) in human neutrophils. Synthetic defensin-1 and -2 (Bachem, Bubendorf CH) stain also positively. Not tested with Defensin-4. A side reaction to elastin has been observed in humans. Other: not tested. Defensins have been described in rabbits (NP-1 to NP-5, NP3a = Corticostatin), and in mice (cryptodin).
Presentation
Lyophilized from PBS, pH 7.2, 5 mg/ml BSA, 0.09% Sodium Azide
Reconstitution
Reconstitute with 0.5ml distilled H2O.
Storage
Store at 4°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Reviews (0)

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Requested From: United States
Date Requested: 10/14/2019