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DCN / Decorin

decorin

DCN / Decorin is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

Gene Name: decorin
Synonyms: DCN, CSCD, Decorin proteoglycan, PG-S2, PG40, Proteoglycan core protein, SLRR1B, Small leucine-rich protein 1B, PGII, PGS2, Bone proteoglycan II, Decorin, DSPG2
Target Sequences: NM_001920 NP_001911.1 P07585

Publications (3)

1
Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts. Coutinho de Souza P, Mallory S, Smith N, Saunders D, Li XN, McNall-Knapp RY, Fung KM, Towner RA. PloS one. 2015 10:e0134276. (WB, Flo; Human, Rat) [Full Text Article] [PubMed:26248280] [PMC:PMC4527837]
2
Databases for technical aspects of immunohistochemistry. Furukawa S, Nagaike M, Ozaki K. Journal of toxicologic pathology. 2017 30:79-107. (IHC; Canine) [Full Text Article] [PubMed:28190929] [PMC:PMC5293696] Related Antibodies: LS-B33.
3
Lung Ablation with Irreversible Electroporation Promotes Immune Cell Infiltration by Sparing Extracellular Matrix Proteins and Vasculature: Implications for Immunotherapy. Masashi Fujimori, Yasushi Kimura, Eisuke Ueshima, Damian E Dupuy, Prasad S Adusumilli, Stephen B Solomon, Govindarajan Srimathveeravalli. Bioelectricity. 2021 September;3:204-214. [Full Text Article] [PubMed:34734168] [PMC:PMC8558078]

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Antibodies (72)
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DCN / Decorin Antibody - Anti-DCN / Decorin antibody IHC of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DCN / Decorin Sheep anti-Human Polyclonal Antibody
Chicken, Bovine, Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
DCN / Decorin Antibody - Anti-DCN / Decorin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DCN / Decorin Mouse anti-Human Monoclonal (3H4-1F4) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
DCN / Decorin Antibody - Anti-Decorin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
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DCN / Decorin Goat anti-Human Polyclonal (aa232-246) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
DCN / Decorin Antibody - Anti-DCN / Decorin antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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DCN / Decorin Rabbit anti-Human Polyclonal Antibody
Rabbit, Mouse, Rat, Pig, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
DCN / Decorin Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma with DCN Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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DCN / Decorin Rabbit anti-Human Polyclonal (aa122-150) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
DCN / Decorin Antibody - Western blot using DCN monoclonal antibody against human DCN recombinant protein. (Expected MW is 32.5 kDa)
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DCN / Decorin Mouse anti-Human Monoclonal (aa263-324) (1G4C5) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
DCN / Decorin Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DCN / Decorin Rabbit anti-Human Polyclonal (C-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
DCN / Decorin Antibody - Anti-DCN / Decorin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DCN / Decorin Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
DCN / Decorin Antibody - Anti-DCN / Decorin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DCN / Decorin Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Rabbit, Dog, Guinea pig, Hamster, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
DCN / Decorin Antibody - Anti-DCN / Decorin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DCN / Decorin Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Rabbit, Dog, Guinea pig, Hamster, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
DCN / Decorin Antibody - Immunofluorescence analysis of MCF-7 cells using DCN antibody. Blue: DAPI for nuclear staining.
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DCN / Decorin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DCN / Decorin ELISA Kit
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Sandwich
96-Well Microplate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$795
DCN / Decorin Protein - Recombinant Decorin By SDS-PAGE
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E. coli
His
37.8 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
DCN / Decorin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.5 - 700 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$840
DCN / Decorin Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DCN / Decorin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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DCN / Decorin Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
500 µg/$1,062
DCN / Decorin Antibody - Decorin antibody IHC-paraffin: Human Mammary Cancer Tissue.
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DCN / Decorin Rabbit anti-Human Polyclonal (aa31-359) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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DCN / Decorin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$379
DCN / Decorin Antibody - Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DCN / Decorin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
DCN / Decorin Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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DCN / Decorin Rabbit anti-Human Polyclonal (aa 20-359) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
DCN / Decorin ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39kD
10 µg/$233; 50 µg/$277; 500 µg/$725; 1 mg/$1,113
DCN / Decorin Antibody - Western blot using DCN monoclonal antibody against human DCN recombinant protein. (Expected MW is 32.5 kDa)
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DCN / Decorin Mouse anti-Human Monoclonal (aa263-324) (5E8E7) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
DCN / Decorin Antibody - Immunohistochemistry of paraffin-embedded Rat lung using Decorin Polyclonal Antibody at dilution of 1:200 (40x lens).
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DCN / Decorin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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DCN / Decorin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Viewing 1-25 of 131 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).