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DCC

deleted in colorectal carcinoma

DCC is a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Gene Name: deleted in colorectal carcinoma
Synonyms: DCC, CRC18, Colorectal tumor suppressor, Colorectal cancer suppressor, IGDCC1, Netrin receptor DCC, Tumor suppressor protein DCC, CRCR1
Target Sequences: NM_005215 NP_005206.2 P43146

☰ Filters
Antibodies (34)
Proteins (3)
Over-Expression Lysate (2)
Primary (34)
Recombinant (1)
DCC (37)
Human (22)
Mouse (24)
Rat (9)
Bat (1)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (1)
Pig (3)
Rabbit (4)
Sheep (1)
Xenopus (3)
Zebrafish (3)
IHC (10)
IHC-P (2)
WB (29)
Flo (1)
ELISA (16)
Func (1)
IF (4)
Peptide-ELISA (3)
rabbit (28)
mouse (6)
IgG (19)
IgG1 (2)
IgG2a,l (1)
IgG2b (3)
monoclonal mc (6)
polyclonal pc (28)
Axel-1 (1)
OTI4A1 (2)
OTI5D10 (2)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (3)
Carrier-free (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (21)
aa1391-1417 (7)
aa643-670 (7)
aa1079-1128 (4)
410-490 aa, Internal (1)
Internal (1)
aa1048-1082 (1)
aa1323-1447 (1)
aa162-178 (1)
aa441-490 (1)
No (37)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
Select
DCC Mouse anti-Human Monoclonal (Axel-1) Antibody
Human
Flo, Func
Unconjugated
100 µg/$561
DCC Antibody - Immunofluorescence analysis of LOVO cells, using DCC Antibody. The picture on the right is blocked with the synthesized peptide.
Select
DCC Rabbit anti-Human Polyclonal (aa441-490) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
DCC Antibody - Western blot of DCC antibody
Select
DCC Rabbit anti-Human Polyclonal (410-490 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
DCC Antibody - DCC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
DCC Rabbit anti-Human Polyclonal (aa643-670) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
DCC Antibody - Mouse Dcc Antibody western blot of mouse Neuro-2a cell line lysates (35 ug/lane). The Dcc antibody detected the Dcc protein (arrow).
Select
DCC Rabbit anti-Mouse Polyclonal (aa1391-1417) Antibody
Mouse
WB
Unconjugated
400 µl/$393
DCC Antibody - DCC antibody. IHC(P): Human Intestinal Cancer Tissue.
Select
DCC Rabbit anti-Human Polyclonal (aa162-178) Antibody
Rabbit, Mouse, Sheep, Bat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
DCC Rabbit anti-Human Polyclonal (aa643-670) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
DCC Rabbit anti-Mouse Polyclonal (aa643-670) (Biotin) Antibody
Mouse
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa643-670) (FITC) Antibody
Mouse
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa643-670) (Azide-free) (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa643-670) (PE) Antibody
Mouse
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa643-670) (APC) Antibody
Mouse
ELISA, IHC, WB
APC Conjugated
200 µl/$952
DCC Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
DCC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
DCC Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using DCC antibody.
Select
DCC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
Select
DCC Rabbit anti-Mouse Polyclonal (aa1391-1417) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
Select
DCC Rabbit anti-Mouse Polyclonal (aa1391-1417) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa1391-1417) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa1391-1417) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa1391-1417) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
DCC Rabbit anti-Mouse Polyclonal (aa1391-1417) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
DCC Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using DCC Polyclonal Antibody at dilution of 1:70.
Select
DCC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
DCC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Select
DCC Mouse anti-Human Monoclonal (aa1323-1447) Antibody
Human
IHC
Unconjugated
100 µg/$896
DCC Antibody - All lanes : Anti-DCC Antibody at 1:1000 dilution Lane 1: U-87 MG whole cell lysates Lane 2: human brain lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 158 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
DCC Rabbit anti-Human Polyclonal (aa1048-1082) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
DCC Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DCC.
Select
DCC Mouse anti-Human Monoclonal (OTI5D10) Antibody
Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 37 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).