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DAD1

defender against cell death 1

Defender of cell death 1 (DAD1) was initially discovered in BHK21 cells as a negative regulator of programmed cell death, a process important for normal organism development and tissue homeostasis. DAD1 was later shown to be a subunit of the mammalian oligosaccharyltransferase complex and is required for its function and structural integrity. Mice lacking DAD1 express abnormal N-linked glycoproteins and undergo increased apoptotic-associated embryonic death. Furthermore, overexpression of DAD1 mRNA is seen in some human hepatocellular carcinomas, indicating it may also play a role in carcinogenesis. It should be noted that DAD1 is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains.

Gene Name: defender against cell death 1
Family/Subfamily: Apoptosis , Not assigned-Other
Synonyms: DAD1, DAD-1, Defender against cell death 1, OST2
Target Sequences: NM_001344 NP_001335.1 P61803

☰ Filters
Antibodies (24)
Proteins (1)
Primary (24)
Recombinant (1)
DAD1 (25)
Human (24)
Mouse (7)
Rat (1)
IHC (5)
IHC-P (1)
WB (23)
ELISA (15)
ICC (1)
IF (1)
rabbit (23)
mouse (1)
Product Group
IHCPlus (1)
IgG (21)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (23)
2B4-C8 (1)
APC Conjugated (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (9)
aa64-92 (7)
C-Terminus (2)
No (25)
GST (1)
Human (1)
Wheat Germ Extract (1)
Purified (1)
DAD1 Antibody - Anti-DAD1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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DAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
DAD1 Antibody - Immunohistochemistry of paraffin-embedded human prostate tissue using DAD1 Antibody at dilution of 1:100
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DAD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
DAD1 Antibody - Western blot of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 12. 4 kDa. Observed band size: 40 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DAD1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
DAD1 Antibody - Western blot of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 12. 4 kDa. Observed band size: 40 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DAD1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
DAD1 Antibody - Western blot of Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit DAD1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 12. 4 kDa. Observed band size: 40 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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DAD1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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DAD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
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DAD1 Rabbit anti-Human Polyclonal (aa64-92) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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DAD1 Rabbit anti-Human Polyclonal (aa64-92) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
Select
DAD1 Rabbit anti-Human Polyclonal (aa64-92) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
DAD1 Rabbit anti-Human Polyclonal (aa64-92) (FITC) Antibody
Human
WB
FITC Conjugated
200 µl/$952
Select
DAD1 Rabbit anti-Human Polyclonal (aa64-92) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
DAD1 Rabbit anti-Human Polyclonal (aa64-92) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
DAD1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µg/$582
Select
DAD1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µg/$582
Select
DAD1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µg/$582
DAD1 Antibody - Detection limit for recombinant GST tagged DAD1 is 0.3 ng/ml as a capture antibody.
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DAD1 Mouse anti-Human Monoclonal (2B4-C8) Antibody
Human
ELISA
Unconjugated
50 µg/$423
Select
DAD1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$649
Select
DAD1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
WB
Unconjugated
100 µg/$748
Select
DAD1 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Human
WB
HRP Conjugated
100 µl/$985
Select
DAD1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
100 µl/$985
Select
DAD1 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Human
WB
FITC Conjugated
100 µl/$985
Select
DAD1 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Human
WB
PE Conjugated
100 µl/$985
DAD1 Antibody - DAD1 Antibody western blot of WiDr cell line lysates (35 ug/lane). The DAD1 antibody detected the DAD1 protein (arrow).
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DAD1 Rabbit anti-Human Polyclonal (aa64-92) Antibody
Human
WB
Unconjugated
400 µl/$393
DAD1 Antibody - Western blot analysis of extracts of various cell lines, using DAD1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5min.
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DAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
DAD1 Protein - 12.5% SDS-PAGE of human DAD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
38.17 kDa
10 µg/$479; 25 µg/$670
Viewing 1-25 of 25 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).