DACH2

dachshund family transcription factor 2

Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression (By similarity). Probably binds to DNA via its DACHbox-N domain.

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Products

Antibodies (20)

Proteins (7)

Type

Over-Expression Lysate (6)

Primary (20)

Recombinant (1)

Target

DACH2 (27)

Reactivity

Human (20)

Mouse (7)

Rat (3)

Chicken (3)

Chimpanzee (6)

Dog (1)

Gibbon (6)

Hamster (3)

Horse (7)

Monkey (4)

Orangutan (3)

Pig (7)

Rabbit (6)

Xenopus (3)

Zebrafish (3)

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Application

IHC (2)

WB (18)

ELISA (9)

Peptide-ELISA (1)

Host

rabbit (19)

goat (1)

Isotype

IgG (14)

Clonality

polyclonal pc (20)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Preservative Free (1)

Unconjugated (9)

Epitope

aa145-173 (7)

C-Terminus (4)

aa525-574 (4)

aa169-181 (1)

Publications

No (27)

Tag

Myc-DDK (Flag) (7)

Species

Human (4)

Source

293T Cells (3)

HEK 293 Cells (4)

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DACH2 Antibody LS-C401582

Antibody:

DACH2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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DACH2 Antibody LS-C404873

Antibody:

DACH2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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DACH2 Antibody LS-C664979

Antibody:

DACH2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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DACH2 Antibody (aa145-173) LS-C320729

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa145-173) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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DACH2 Antibody (aa145-173, Biotin) LS-C234404

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa145-173) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

DACH2 Antibody (aa145-173, FITC) LS-C234405

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa145-173) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

DACH2 Antibody (aa145-173, Azide-free, HRP) LS-C249790

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa145-173) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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DACH2 Antibody (aa145-173, PE) LS-C234406

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa145-173) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

DACH2 Antibody (aa145-173, APC) LS-C234403

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa145-173) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• PE
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • PE
  • APC

Select

DACH2 Antibody (aa169-181) LS-C61729

Antibody:

DACH2 Goat anti-Human Polyclonal (aa169-181) Antibody

Reactivity:

Mouse, Dog, Pig, Horse, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

DACH2 Antibody (aa525-574) LS-C29920

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa525-574) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

DACH2 Antibody (aa525-574, HRP) LS-C427873

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa525-574) (HRP) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rabbit, Mouse, Rat, Gibbon, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

DACH2 Antibody (aa525-574, Biotin) LS-C427871

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa525-574) (Biotin) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rabbit, Mouse, Rat, Gibbon, Human, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

DACH2 Antibody (aa525-574, FITC) LS-C427872

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa525-574) (FITC) Antibody

Reactivity:

Xenopus, Chicken, Zebrafish, Pig, Horse, Rabbit, Mouse, Rat, Gibbon, Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DACH2 Antibody (C-Terminus) LS-C201256

Antibody:

DACH2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

DACH2 Antibody (C-Terminus, HRP) LS-C427876

Antibody:

DACH2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Hamster, Pig, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

DACH2 Antibody (C-Terminus, Biotin) LS-C427874

Antibody:

DACH2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Hamster, Pig, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

DACH2 Antibody (C-Terminus, FITC) LS-C427875

Antibody:

DACH2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Hamster, Pig, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

DACH2 Antibody (aa145-173) LS-C167261

Antibody:

DACH2 Rabbit anti-Human Polyclonal (aa145-173) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

DACH2 Antibody (Preservative Free) LS-C814789

Antibody:

DACH2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

Human DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92974

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.8 kDa

Price:

20 µg/$150

Select

Human DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92975

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47 kDa

Price:

20 µg/$150

Select

Human DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92976

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.1 kDa

Price:

20 µg/$215

Select

DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108002

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

65.1 kDa

Price:

100 µg/$710

Select

DACH2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125813

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.8 kDa

Price:

100 µg/$494

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