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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CYR61 Antibody (aa176‑281) LS‑C64183
CYR61 antibody LS-C64183 is an unconjugated rat monoclonal antibody to mouse CYR61. Validated for ELISA, IHC and WB.
Antibody
Catalog
Size
Price
LS-C64183-100
100 µg (0.5 mg/ml)
$620

Popular CYR61 Products

Detection of cleaved CYR61 in MDA-MB-231 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Applications: IHC, IHC - Paraffin, Western blot

Product Description

CYR61 antibody LS-C64183 is an unconjugated rat monoclonal antibody to mouse CYR61. Validated for ELISA, IHC and WB.

Specifications

Target
Mouse CYR61
Synonyms
CYR61, GIG1, IGFBP10, Protein CYR61, CCN family member 1, CCN1, IBP-10, IGF-binding protein 10, IGFBP-10, Protein GIG1
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC (25 µg/ml)
  • Western blot (2 µg/ml)
  • ELISA (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CYR61 antibody was raised against e. coli-derived rmCyr61. (aa 176 - 281).
Epitope
aa176-281
Specificity
Recognizes mouse Cyr61.
Usage
Suitable for use in Direct ELISA, Immunohistochemistry and Western Blot. Direct ELISA: 0.5-1.0 ug/ml. Detection limit is ~5 ng/well. Western Blot: 2 ug/ml. Immunohistochemistry: 25 ug/ml.
Presentation
Lyophilized from PBS, 5% Trehalose
Reconstitution
200 µl Sterile PBS
Storage
Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CYR61
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. O00622 NM_001554 NP_001545.2


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Requested From: United States
Date Requested: 11/13/2018

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