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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTSK / Cathepsin K Antibody IHC‑plus™ LS‑B2512 Best Seller
Note: This antibody replaces LS-C48544
Cathepsin K antibody LS-B2512 is an unconjugated rabbit polyclonal antibody to Cathepsin K (CTSK) from human, mouse, rat and other species. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B2512-50
50 µg (0.5 mg/ml)
$495

Popular CTSK / Cathepsin K Products

Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Human
Applications: Western blot, ELISA
Anti-CTSK / Cathepsin K antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2531 concentration 5 ug/ml.
Species: Rat, Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

Cathepsin K antibody LS-B2512 is an unconjugated rabbit polyclonal antibody to Cathepsin K (CTSK) from human, mouse, rat and other species. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.

Specifications

Target
Rat CTSK / Cathepsin K
Synonyms
CTSK, Cathepsin K, Cathepsin K (pycnodysostosis), Cathepsin O1, Cathepsin O2, Cathepsin X, CTSO2, PKND, Procathepsin K, PYCD, Cathepsin O, CTS02, CTSO1
Host
Rabbit
Reactivity
Rat, Human, Mouse, Pig, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (0.5 - 4 µg/ml)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide surrounding amino acid 321 of rat cathepsin K.
Specificity
The antibody detects proform (43 kD) and the mature form (29 kD) of cathepsin K.
Usage
Immunohistochemistry: LS-B2512 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2512 was determined to be 2.5 ug/ml.
Presentation
PBS, pH 7.2, 0.5% BSA, 30% glycerol, 5 mM EDTA, 0.03% proclin
Storage
Short term: -20°C; Long term: -70°C.
Restrictions
For research use only.
About CTSK / Cathepsin K
CTSK / Cathepsin K is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. P43235 NM_000396 NP_000387.1


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Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.

Western blot

Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.
Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.

Western blot

Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.
Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.

Western blot

Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.
Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.

Western blot

Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.
Western blot of Cathepsin K antibody LS-B2512 with rat kidney lysates.

Requested From: United States
Date Requested: 10/23/2018

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