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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTSK / Cathepsin K Antibody (clone 2F1) IHC‑plus™ LS‑B4308
Note: This antibody replaces LS-C104929
Cathepsin K antibody LS-B4308 is an unconjugated mouse monoclonal antibody to human Cathepsin K (CTSK). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B4308-50
50 µg (1 mg/ml)
$485

Popular CTSK / Cathepsin K Products

Antibody
Species: Human
Applications: Western blot, ELISA
Anti-CTSK / Cathepsin K antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2512 concentration 5 ug/ml.
Species: Rat, Human, Mouse, Pig, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Anti-CTSK / Cathepsin K antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2531 concentration 5 ug/ml.
Species: Rat, Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

Cathepsin K antibody LS-B4308 is an unconjugated mouse monoclonal antibody to human Cathepsin K (CTSK). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About CTSK / Cathepsin K
CTSK / Cathepsin K is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. P43235 NM_000396 NP_000387.1

CTSK Antibody, Cathepsin K Antibody, Cathepsin K (pycnodysostosis) Antibody, Cathepsin O1 Antibody, Cathepsin O2 Antibody, Cathepsin X Antibody, CTSO2 Antibody, PKND Antibody, Procathepsin K Antibody, PYCD Antibody, Cathepsin O Antibody, CTS02 Antibody, CTSO1 Antibody


Specifications

Target
Human CTSK / Cathepsin K
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [2F1]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:500 - 1:1000)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CTSK (AAH16058, 220 a.a. ~ 331 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Usage
Western Blot (Transfected lysate) - positive control transfected 293T cell line. Sandwich ELISA (Recombinant protein).
Presentation
PBS, pH 7.4
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Western blot

Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.
Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Western blot

Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.
Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Western blot

Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.
Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Immunohistochemistry

Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.
Anti-CTSK / Cathepsin K antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4308 concentration 5 ug/ml.

Western blot

Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.
Western blot of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody, clone 2F1.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged CTSK is approximately 3 ng/ml as a capture antibody.

Requested From: United States
Date Requested: 8/15/2018

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