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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CTSB / Cathepsin B Antibody (Internal) LS‑C368581
Cathepsin B antibody LS-C368581 is an unconjugated rabbit polyclonal antibody to Cathepsin B (CTSB) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C368581-30
30 µl (1 mg/ml)
$205
LS-C368581-100
100 µl (1 mg/ml)
$245
LS-C368581-200
200 µl (1 mg/ml)
$305

Popular CTSB / Cathepsin B Products

Anti-CTSB / Cathepsin B antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3313 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Western blot of CTSB pAb in extracts from mouse brain tissue.
Species: Human, Mouse, Rat
Applications: IHC, Western blot

Product Description

CTSB / Cathepsin B Antibody (Internal) for WB/Western LS-C368581

Specifications

Target
Human CTSB / Cathepsin B
Synonyms
CTSB, Cathepsin B1, Cathepsin B, Cathepsins B, CPSB, Cysteine protease, Preprocathepsin B, APP secretase, APPS
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human Cathepsin B.
Blocking Peptide
LS-E40900 - Lyophilized - 1 mg - $145.00
Immunizing peptide used to generate LS-C368581. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Recognizes endogenous levels of Cathepsin B protein.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only.
About CTSB / Cathepsin B
Cathepsin B is a lysosomal cysteine proteinase synthesized as a zymogen of 39-47 kilodaltons (kD), which is subsequently converted into an active single- chain form of 33 kD (CB33) and, by additional processing, into the active 2-chain form containing a heavy chain of 27-29 kD (CB(27-29)) and a light chain of 4-6 kD. P07858 NM_001908 NP_001899.1


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Images

Western blot

Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.
Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.

Western blot

Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.
Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.

Western blot

Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.
Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.

Western blot

Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.
Western blot analysis of Cathepsin B expression in A549 (A); HT1080 (B); mouse heart (C) whole cell lysates.

Requested From: United States
Date Requested: 10/21/2018

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