CD35 antibody LS-C389530 is an unconjugated mouse monoclonal antibody to CD35 (CR1) from human, baboon, cynomolgus monkey and other species. Validated for ELISA, Flow, IF, IHC, IP and WB.
Human, Baboon, Cynomolgus monkey, Rhesus monkey
(tested or 100% immunogen sequence identity)
Protein G purified
Also available Unmodified
- IHC - Paraffin (1:1)
- Western blot
- Flow Cytometry
- (applications tested for the base form of this product only)
See our complete line of Immunohistochemistry Reagents
including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
CR1 / CD35 antibody was raised against intact human monocytes were used as the immunogen for this CD35 antibody.
Human CR1 / CD35
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1), or CD35. The antibody is specific for a site on CD35 that is distal from the C3b-binding site, so that it is unable to block CD35 activity. The CD35 antibody is highly specific and shows no cross-reaction with CR2. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This antibody labels follicular dendritic cells and follicular dendritic cell sarcoma. ELISA: Order BSA-free format for coating.
PBS, 0.01% BSA, 0.05% sodium azide
Store at 2°C to 8°C.
For research use only.