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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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CR1 / CD35 Antibody (clone E11, Ready-to-Use) LS-C389530

CD35 antibody E11 immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.

CR1 / CD35 Antibody (clone E11, Ready-to-Use) LS-C389530

Antibody:
Mouse Monoclonal to Human CR1 / CD35
Application:
IHC, IHC-P, IF, WB, IP, Flo, ELISA
Reactivity:
Human, Baboon, Cynomolgus monkey, Rhesus monkey
Format:
Unconjugated, Ready-to-Use
Other formats:
Price
Catalog Number
$465 
LS-C389530-7
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human CR1 / CD35
Application:
IHC, IHC-P, IF, WB, IP, Flo, ELISA
Reactivity:
Human, Baboon, Cynomolgus monkey, Rhesus monkey
Format:
Unconjugated, Ready-to-Use
Other formats:

Specifications

Description
CD35 antibody LS-C389530 is an unconjugated mouse monoclonal antibody to CD35 (CR1) from human, baboon, cynomolgus monkey and other species. Validated for ELISA, Flow, IF, IHC, IP and WB.

Target
Human CR1 / CD35
Host
Mouse
Reactivity
Human, Baboon, Cynomolgus monkey, Rhesus monkey (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
E11
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Ready-to-Use. Also available Unmodified or Azide-free.
Applications
  • IHC
  • IHC - Paraffin (1:1)
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CR1 / CD35 antibody was raised against intact human monocytes were used as the immunogen for this CD35 antibody.
Specificity
Human CR1 / CD35
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1), or CD35. The antibody is specific for a site on CD35 that is distal from the C3b-binding site, so that it is unable to block CD35 activity. The CD35 antibody is highly specific and shows no cross-reaction with CR2. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This antibody labels follicular dendritic cells and follicular dendritic cell sarcoma. ELISA: Order BSA-free format for coating.
Presentation
PBS, 0.01% BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CR1 / CD35
P17927 NM_000651 NP_000642.3

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Reactivity: Human
Range: 0.156-10 ng/ml
Reactivity: Human
Range: 0.156-10 ng/ml
Reactivity:
Range: 1.23-100 ng/ml
Reactivity: Human
Range: 15.6-1000 pg/ml

Requested From: United States
Date Requested: 5/26/2019
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