Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Complement C9 antibody was raised against synthetic peptide C-ETKGEKNFRTEH from an internal region of human Complement C9 (NP_001728.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Chimpanzee, Monkey (92%); Rat (75%); Mouse (67%).
Human Complement C9.
Peptide ELISA: antibody detection limit dilution 1:4000. Western blot: Approx 70kD band observed in Human Placenta, Kidney and Liver lysates (calculated MW of 63.2kD according to NP_001728.1). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 1-3 ug/ml.
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.