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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Complement C6 Antibody (C‑Terminus, clone 056B‑214.2.4.2) IHC‑plus™ LS‑B3294
Note: This antibody replaces LS-C45004
Complement C6 antibody LS-B3294 is an unconjugated mouse monoclonal antibody to human Complement C6. Validated for ELISA, Flow and IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3294-50
50 µg (1 mg/ml)
Unavailable

Popular Complement C6 Products

Western blot Image
Species: Human
Applications: Western blot
Western blot Image
Species: Human
Applications: Western blot, Immunoprecipitation, ELISA
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with C6 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Antibody
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA

Product Description

Complement C6 antibody LS-B3294 is an unconjugated mouse monoclonal antibody to human Complement C6. Validated for ELISA, Flow and IHC. Tested on 20 paraffin-embedded human tissues.
About Complement C6
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. P13671 NM_000065 NP_000056.2

C6 Antibody, Complement component C6 Antibody, Complement C6 Antibody, Complement component 6 Antibody


Specifications

Target
Human Complement C6
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [056B-214.2.4.2]
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Complement C6 antibody was raised against purified human C6.
Epitope
C-Terminus
Specificity
Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
Usage
Immunohistochemistry: LS-B3294 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3294 was determined to be 10 ug/ml. Histology Positive Control Tissue: Kidney from post streptococcal glomerulonephritis patients.
Presentation
Borate buffered saline, 0.09% sodium azide. Sourced in Ascites.
Storage
4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.

Immunohistochemistry

Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.
Anti-C6 / Complement C6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3294 concentration 10 ug/ml.


Requested From: 
Date Requested: 6/24/2018

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