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Catalog Number Size Price
LS-C388109-100 100 µg $506 
Complement C5a Antibody - IHC-P: C5a antibody testing of rat spleen tissue
Complement C5a Antibody - IHC-P: C5a antibody testing of rat liver tissue
Complement C5a Antibody - IHC-P: C5a antibody testing of mouse spleen tissue
Complement C5a Antibody - Western blot testing of C5a antibody and Lane 1: rat liver; 2: mouse liver; 3: (m) NIH3T3; 4: (m) HEPA; 5: (r) PC12 lysate; Predicted/Observed size: 115KD
Complement C5a Antibody - IHC-P: C5a antibody testing of rat spleen tissue
Complement C5a Antibody - IHC-P: C5a antibody testing of rat liver tissue
Complement C5a Antibody - IHC-P: C5a antibody testing of mouse spleen tissue
Complement C5a Antibody - Western blot testing of C5a antibody and Lane 1: rat liver; 2: mouse liver; 3: (m) NIH3T3; 4: (m) HEPA; 5: (r) PC12 lysate; Predicted/Observed size: 115KD
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Polyclonal Rabbit anti‑Rat Complement C5a Antibody (aa1‑18, IHC, WB) LS‑C388109

Polyclonal Rabbit anti‑Rat Complement C5a Antibody (aa1‑18, IHC, WB) LS‑C388109

Antibody:
Complement C5a Rabbit anti-Rat Polyclonal (aa1-18) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Rat, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$506
LS-C388109-100
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Complement C5a Rabbit anti-Rat Polyclonal (aa1-18) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Rat, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
Complement C5a antibody LS-C388109 is an unconjugated rabbit polyclonal antibody to Complement C5a (aa1-18) from rat. It is reactive with mouse and rat. Validated for IHC and WB.
Target
Rat Complement C5a
Synonyms
C5a
Host
Rabbit
Reactivity
Rat, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from the N-Terminus of rat Complement 5a (DLQLLHQKVEEQAAKYKH, aa1-18 of UniProt P08650). Percent identity by BLAST analysis: Rat (100%); Mouse (78%); Human (56%).
Epitope
aa1-18
Specificity
Rat Complement C5a
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/4/2021