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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Complement C5 Antibody LS‑C147222
Complement C5 antibody LS-C147222 is an unconjugated goat polyclonal antibody to human Complement C5. Validated for ID.
Antibody
Catalog
Size
Price
LS-C147222-1
1 ml
$305

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Product Description

Complement C5 antibody LS-C147222 is an unconjugated goat polyclonal antibody to human Complement C5. Validated for ID.
About Complement C5
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. P01031 NM_001735 NP_001726.2

C5 Antibody, Anaphylatoxin C5a analog Antibody, CPAMD4 Antibody, Complement C5 Antibody, Complement component 5 Antibody


Specifications

Target
Human Complement C5
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with FITC.
Purification
Immunoaffinity absorbed
Modifications
Unmodified
Applications
  • Immunodiffusion
  • (applications tested for the base form of this product only)
Immunogen
Complement C5 antibody was raised against human C5
Specificity
Human Complement C5. The reactivity of the antiserum is restricted to C5. In immunoelectrophoresis and radial immunodiffusion (Ouchterlony), using various antiserum concentrations against fresh normal human plasma a single precipitin line is obtained which shows a reaction of identity with the precipitin line obtained with purified C5 protein. No reaction is obtained with any other plasma protein component or serum. Cross-reactivity The antiserum does not cross react with any other component of human plasma. Inter-species cross- reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.
Usage
This product is intended for use in precipitating techniques as immunoelectrophoresis and single or double radial immunodiffusion to identify the presence of C5 containing complexes in human plasma or other body fluids or to determine its concentration. The presence of non precipitating antibodies has not been assayed. This does not exclude the use of the antiserum in more sensitive non-precipitating antibody-binding techniques if proper controls are included.
Presentation
Lyophilized antiserum
Reconstitution
1 ml Sterile distilled water 1 ml
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/22/2018

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