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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CNTN1 / gp135 / Contactin 1 Antibody (aa81‑130, Biotin) LS‑C466249
Contactin 1 antibody LS-C466249 is a biotin-conjugated rabbit polyclonal antibody to Contactin 1 (CNTN1 / gp135) from human, rat, bovine and other species. Validated for WB.
Catalog
Size
Price
LS-C466249-100
100 µl (1 mg/ml)
$385

Popular CNTN1 / gp135 / Contactin 1 Products

CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Rat, Bovine, Dog, Guinea pig, Horse, Pig
Applications: Western blot
Anti-CNTN1 / gp135 / Contactin 1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10585 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Guinea pig, Pig
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-CNTN1 / gp135 / Contactin 1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10586 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Horse, Pig
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Human, Rat
Applications: IHC, Western blot

Product Description

Contactin 1 antibody LS-C466249 is a biotin-conjugated rabbit polyclonal antibody to Contactin 1 (CNTN1 / gp135) from human, rat, bovine and other species. Validated for WB.
About CNTN1 / gp135 / Contactin 1
Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Q12860 NM_001843 NP_001834.2

CNTN1 Antibody, Contactin Antibody, Contactin 1 Antibody, Glycoprotein gp135 Antibody, gp135 Antibody, Neural cell surface protein F3 Antibody, Contactin-1 Antibody


Specifications

Target
Human CNTN1 / gp135 / Contactin 1
Host
Rabbit
Reactivity
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Rat, Bovine, Dog, Guinea pig, Horse, Pig (tested or 100% immunogen sequence identity)
Predicted
Mouse, Bat, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide located between aa81-130 of human CNTN1 (Q12860, NP_001834). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Rat, Dog, Bovine, Horse, Pig, Guinea pig (100%); Mouse, Elephant, Bat, Rabbit (92%).
Epitope
aa81-130
Specificity
Human CNTN1 / Contactin 1
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
CNTN1 / Contactin 1 antibody LS-C116853 Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 8/19/2018

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