Reactivity
Virus
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated.
Also available conjugated with
FITC.
Specificity
Recognizes Cytomegalovirus glycoprotein B late neutralizing antigen. Cytomegalovirus is an enveloped double stranded DNA virus which in humans (HCMV) is commonly known as human herpesvirus 5 (HHV-5). Glycoprotein B (gB) is the main antigenic protein within the envelope of HCMV. It is required for HCMV mediated membrane fusion along with the gH / gL complex. The unprocessed precursor of HCMV gB is 906 amino acids in length, with a MW of approximately 100kD. Reacts with MRC-5 infected cells but not uninfected cells. Has been found to be neutralizing.