CLEC4M / L-SIGN / CD299

C-type lectin domain family 4, member M

CLEC4M / L-SIGN / CD299 is a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.

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Products

Antibodies (45)

Proteins (10)

ELISA Kits (1)

Type

Over-Expression Lysate (4)

Primary (45)

Recombinant (6)

Sandwich (1)

Target

CLEC4M / L-SIGN / CD299 (56)

Reactivity

Human (46)

Mouse (10)

Rat (6)

Chimpanzee (12)

Gibbon (6)

Monkey (6)

Orangutan (3)

Application

IHC (16)

IHC-P (10)

WB (38)

Flo (3)

ELISA (10)

Host

rabbit (33)

mouse (12)

Product Group

IHCPlus (1)

Isotype

IgG (15)

IgG,k (1)

IgG1 (3)

IgG1,k (1)

IgG2b (2)

IgG3,l (6)

Clonality

monoclonal mc (11)

polyclonal pc (32)

recombinant monoclonal rmc (2)

Clone

16E7 (2)

8A1B3 (1)

OTI10C3 (2)

OTI7D12 (2)

Format

96-Well Microplate (1)

APC (1)

APC Conjugated (2)

Biotin Conjugated (7)

Carrier-free (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (2)

Unconjugated (18)

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Epitope

aa242-399 (8)

N-Terminus (4)

aa143-192 (4)

aa323-372 (4)

aa51-100 (4)

aa74-329 (4)

DC-SIGNR (2)

aa285-394 (1)

Publications

No (56)

Sample Type

Cell Culture Supernatants (1)

Plasma (1)

Serum (1)

Tag

8His-DDK (Flag), N-terminus (1)

Fc (1)

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (8)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Human (1)

Human Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

Select

Human CLEC4M / L-SIGN / CD299 Protein (Recombinant His-T7) (aa242-399) - LS-G14199

Source:

E. coli

Tag:

His-T7

Molecular Weight:

22.3 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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CLEC4M / L-SIGN / CD299 Antibody (aa51-100) LS-C31891

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa51-100) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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CLEC4M / L-SIGN / CD299 Antibody (aa51-100, HRP) LS-C443658

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa51-100) (HRP) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

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CLEC4M / L-SIGN / CD299 Antibody (aa51-100, Biotin) LS-C443656

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa51-100) (Biotin) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

CLEC4M / L-SIGN / CD299 Antibody (aa51-100, FITC) LS-C443657

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa51-100) (FITC) Antibody

Reactivity:

Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CLEC4M / L-SIGN / CD299 Antibody (aa323-372) LS-B11484

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa323-372) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

CLEC4M / L-SIGN / CD299 Antibody (aa323-372, HRP) LS-C443661

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa323-372) (HRP) Antibody

Reactivity:

Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

CLEC4M / L-SIGN / CD299 Antibody (aa323-372, Biotin) LS-C443659

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa323-372) (Biotin) Antibody

Reactivity:

Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

CLEC4M / L-SIGN / CD299 Antibody (aa323-372, FITC) LS-C443660

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa323-372) (FITC) Antibody

Reactivity:

Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

CLEC4M / L-SIGN / CD299 Antibody (aa242-399, HRP) LS-C710213

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal (aa242-399) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$331; 200 µl/$383; 500 µl/$556; 1 ml/$665; 2 ml/$901; 5 ml/$1,511

Select

CLEC4M / L-SIGN / CD299 Antibody (clone 8A1B3) LS-C828287

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (8A1B3) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µg/$459

Select

CLEC4M / L-SIGN / CD299 Antibody (DC-SIGNR, clone 16E7) LS-C777407

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Recombinant Monoclonal (DC-SIGNR) (16E7) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P

Format:

Unconjugated

Price:

0.2 mg/$540

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CLEC4M / L-SIGN / CD299 Antibody (aa74-329, clone OTI7D12) LS-C795253

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (aa74-329) (OTI7D12) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

CLEC4M / L-SIGN / CD299 Antibody (aa74-329, clone OTI7D12, Carrier-free) LS-C792336

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (aa74-329) (Carrier-free) (OTI7D12) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

CLEC4M / L-SIGN / CD299 Antibody LS-C664641

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

CLEC4M / L-SIGN / CD299 Antibody LS-C813804

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

CLEC4M / L-SIGN / CD299 Antibody (aa74-329, clone OTI10C3) LS-C795249

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (aa74-329) (OTI10C3) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

100 µl/$434

Select

CLEC4M / L-SIGN / CD299 Antibody (aa74-329, clone OTI10C3, Carrier-free) LS-C799675

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (aa74-329) (Carrier-free) (OTI10C3) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

CLEC4M / L-SIGN / CD299 Antibody LS-C781259

Antibody:

CLEC4M / L-SIGN / CD299 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

CLEC4M / L-SIGN / CD299 Antibody (aa285-394) LS-C306989

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (aa285-394) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

CLEC4M / L-SIGN / CD299 Antibody (HRP) LS-C541511

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

CLEC4M / L-SIGN / CD299 Antibody (Biotin) LS-C521378

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

CLEC4M / L-SIGN / CD299 Antibody (FITC) LS-C531421

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

CLEC4M / L-SIGN / CD299 Antibody (APC) LS-C513163

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC

Select

CLEC4M / L-SIGN / CD299 Antibody (DC-SIGNR, clone 16E7) LS-C777406

Antibody:

CLEC4M / L-SIGN / CD299 Mouse anti-Human Recombinant Monoclonal (DC-SIGNR) (16E7) Antibody

Reactivity:

Human

Applications:

Flo, IHC

Format:

Unconjugated

Price:

0.2 mg/$540

Viewing 1-25 of 56 product results

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