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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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CLCN4 / CLC‑4 Antibody (C‑Terminus) LS‑C6129
CLC-4 antibody LS-C6129 is an unconjugated rabbit polyclonal antibody to CLC-4 (CLCN4) from human, mouse and rat. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C6129-100
100 µl
$725

Popular CLCN4 / CLC-4 Products

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Applications: ICC, Immunofluorescence, Western blot, ELISA

Product Description

CLC-4 antibody LS-C6129 is an unconjugated rabbit polyclonal antibody to CLC-4 (CLCN4) from human, mouse and rat. Validated for ELISA and WB.
About CLCN4 / CLC-4
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. P51793 NM_001830 NP_001821.2

CLCN4 Antibody, ClC-4 Antibody, Chloride channel 4 Antibody, Chloride channel protein 4 Antibody, Chloride transporter ClC-4 Antibody, ClC-4A Antibody, CLC4 Antibody


Specifications

Target
Rat CLCN4 / CLC-4
Host
Rabbit
Reactivity
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:50000)
Immunogen
CLCN4 / CLC-4 antibody was raised against a 13 AA Peptide sequence near the C-terminus of rat CLC-4 (1). The peptide was coupled to KLH.
Epitope
C-Terminus
Specificity
The 13 AA rat CLC41-P control peptide is 100% conserved in mouse, rat and human CLC-4. No significant sequence homology is detected with other CLCs or other proteins. Actual cross-reactivity of antibodies in various species has not been studied. There is a very high degree of protein homology among CLC-3, CLC-4 and CLC-5. However, CLC41-P peptide has very little sequence homology with CLC-3 and CLC-5. Anti-rat CLC41 antibodies were checked against the corresponding CLC-3 and CLC-5. These peptides are also available to confirm specificity of antibodies.
Usage
Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000 for neat serum and 1-10 ug/ml for affinity pure antibody using ECL. ELISA:1:10000-1:50000 for neat serum and 0.5-1 ug/ml for affinity purified. Control peptide can be used to coat ELISA plates at 1 ug/ml.
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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